Stimuli-responsive surfaces

Mendes PM (2008) Stimuli-responsive surfaces for bio-applications. Chem Soc Rev 37 2512-2529... 

Xu H, Norsten TB, Uzun O, Jeoung E, Rotello VM. Stimuli responsive surfaces through recognition-mediated polymer modification. Chem Commun 2005 5157-5159. 

Stimuli-responsive surfaces were synthesized with block copolymer brashes... 

Control over the stmcturation process permits not only the modification of the dimensions of a particular morphology but also order-order transitions between two different microphases. Equally, these transitions can be accompanied by macrophase separation, thus leading to hierarchically structured surfaces. Finally, this chapter analyzes the role of BCP blends in a few selected examples. Surface patterning, the elaboration of ACs or nanostructured hydrogels, or the fabrication of sophisticated stimuli-responsive surfaces are a few of the applications that currently take advantage of these polymeric systems. 

J. Rodriguez-Hernandez, E. Ibarboure, E. Papon, Surface segregation of polypeptide-based block copolymer micelles an approach to engineer nanostructured and stimuli responsive surfaces, European Polymer Journal 47 (2011) 2063-2068. 

The ability to control the interaction between a wide diversity of biomolecules with surfaces can be also exploited as an effective way to develop reagentless, sensitive, reusable, and real-time biosensors [51-56]. Such sophisticated biosensors are expected to impact a wide range of applications, from clinical diagnosis[57] and environmental monitoring [58] to forensic analysis [59]. Another significant potential application of dynamic surfaces is in bioseparation of proteins and other biomolecules for basic life science research, as well as industrial applications [60-63]. With the rapid development of recombinant proteins in the treatment of various human diseases, the dynamic surface-based bioseparation systems could meet the demand for more reliable and efficient protein purification methods [64]. Stimuli-responsive surfaces are also expected to play a crucial role in the search for more controllable and precise drug delivery systems [65]. 

Ayres, N. Cyrus, C. D. Brittain, W. J. Stimuli-responsive surfaces using polyampholyte polymer brushes prepared via atom transfer radical polymerization. Langmuir 2007,23, 3744-3749. 

Stimuli responsive surface Polymers (responsive, biocompatible, conductive, etc.) Smart responsive surfaces and scaffolds Batra et al. (2006), Wu and Sailor (2009), Fan et al. (2009), Segal et al. (2009), Kashanian... 

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