Stimuli-responsive amphiphilic

Stimulated emission, 14 660—661, 662, 669 Stimuli-responsive amphiphilic polymers,... 

Mertoglu M, Gamier S, Laschewsky A, Skrabania K, Storsberg J. Stimuli responsive amphiphilic block copolymers for aqueous media synthesised via reversible addition fragmentation chain transfer polymerisation (RAFT). Polymer 2005 46(18) 7726-40. 

Smith AE, Xu XW, Mccormick CL. Stimuli-responsive amphiphilic (co)polymers via RAFT polymerization. Prog Polym Sci 2010 35 45-93. 

ELP-based triblock copolypeptides have also been used to produce stimulus-responsive micelles, and Chaikof and coworkers envisioned the possible application of these micelles as controlled drug delivery vehicles. These amphiphilic triblock copolymers were constructed from two identical hydrophobic ELP endblocks and a hydrophilic ELP midblock. Below the transition temperature, loose and monodispersed micelles were formed that reversibly contracted upon heating, leading to more compact micelles with a reduced size [90]. 

Timg R, Ln X, Xia H (2014) A facile mechanophore functionalization of an amphiphilic block copolymCT towards remote ultrasound and redox dual stimulus responsiveness. Chem Commun 50 3575-3578... 

A sensor is a system that displays a readily detectable response in the presence of a specific analyte. Indeed, stimulus-responsive vesicles have been tailor-made to function as highly specific sensors. The overwhelming majority of vesicle-based sensors are based on a very simple type of amphiphile polydiacetylenes. These polymeric amphiphiles are easily formed from simple diacelylene amphiphiles by in situ photopolymerization of vesicles. If the vesicles are additionally equipped with ligand or receptor groups, the absorbance and fluorescence of the conjugated polymer backbone is highly sensitive to the presence of metal ions, anions, and small as well as large... 

Another possibility for azo-polysiloxane applications is to obtain photo-sensible micelles [15-18]. The interest for this application is explained by the possibility to use polymeric micellar aggregates for controlled release of substances such as drugs [19, 20]. There are few reports on the use of light as an external stimulus for small amphiphilic molecules by incorporahug the azobeuzeue chromophore iuto surfactant [16] or for light-responsive micellar aggregates formed by amphiphilic block copolymers [17,18]. 

Self-organization of amphiphilic (co)polymers has resulted in assemblies such as micelles, vesicles, fibers, helical superstructures, and macroscopic tubes [174, 175]. These nanoscale to macroscale morphologies are of interest in areas ranging from material science to biology [176]. Stimuli-responsive versions of these assemblies are likely to further enhance their scope as smart materials. Thermo- or pH-sensitive polymer micelles [177] and vesicles [178] have been reported in which the nature of the functionality at the corona changes in response to the stimulus. Some attention has been also paid to realize an environment-dependent switch from a micelle-type assembly with a hydrophilic corona to an inverted micelle-type assembly with a lipophilic corona [179]. 

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