St. Thomas’ Hospital

E. G. M. POWER BSc, PhD, Lecturer in Microbiology, Department ofMicrobiology, United Medical and Dental Schools, St. Thomas Hospital, Lambeth Palace Road, London... 

Another example of a biomaterial is the intraocular lens, which have been commonly used to treat cataracts. They were traditionally made of inflexible materials, but more recently consist of poly(methyl methacrylate) and soft flexible materials such as silicone and acrylic. The first person to successfully implant an intraocular lens was Sir Harold Riley at the St Thomas Hospital in London in 1949. The first lenses were made of glass, were heavy, and carried several risks including infection, inflammation, loosening of the lens, lens rotation, and night time halos (Thompson, 2007). These problems, now less frequent, still occur today in a small fraction of more than one million intraocular lenses that are implanted annually in the USA. 

Guys St. Thomas Hospital Cardiology Department London UK... 

Glucose 10% is generally readily available in a hospital environment. Supplies of haem arginate (human hemin), trade name Normosang may be obtained from Orphan Europe during office hours and out of hours from St Thomas Hospital, London. 

Dr Karalliedde was formerly Senior Lecturer and Honorary Consultant Anaesthetist at the United Medical Dental Schools of Guy s St Thomas Hospitals, London, UK and Medical Toxicologist at Guy s Poisons Unit and National Poisons Information Service, Guy s St Thomas NHS Foundation Trust, London, UK. 

In a 5-year toxicological study of traditional remedies and food supplements carried out by the Medical Toxicology Unit at Guy s and St. Thomas Hospital, London, 1297 symptomatic enquiries by medical professionals were evaluated (28). Of these, an association was considered to have been confirmed, probable, or possible in 12, 35, and 738 cases respectively. Ten of the confirmed cases were related to Chinese or Indian herbal remedies. As a result of these findings, in October 1996 the UK Committee on Safety of Medicines extended its yellow card scheme for adverse drug reaction reporting to include unhcensed herbal remedies, which are marketed mostly as food supplements in the UK (the scheme had always apphed to hcensed herbal medicines) (29,30). This was an important milestone in herbal pharmacovigilance. 

Danetz JS, Clemo HF, Davies RD, Embrey RP, Damiano RJ Jr, Baumgarten CM (1999) Age-related effects of St Thomas Hospital cardioplegic solution on isolated cardiomyo-cyte cell volume. J Thorac Cardiovasc Surg 118 467-476... 

Dr. Michael J. Curtis (Rayne Institute, St Thomas Hospital, UK)... 

For more information or to join the EAPCCT contact EAPCCT General Secretary, National Poison Information Service, Guy s St. Thomas Hospital Trust, Medical Toxicology Unit, Avonley Road, London SE14 5ER, U.K. Tel. 44-207-771-5310, Fax 44-207-771-5309, E-mail alex.campbell gstt.sthames.nhs.uk, Web site www.eapcct.org. 

Department of Immunology The Rayne Institute St. Thomas Hospital London SE1 7EH England... 

Rapid progress in gastroenterological research was initiated by the discovery by William Front (Guy s and St. Thomas hospitals London), in 1823, of the presence of inorganic, hydrochloric acid in the stomach and by Ivan P. Pavlov (Saint-Petersburg) in 1890, of neuro-reflex stimulation of secretion of this acid that was awarded Nobel Prize in 1904. Then, James W. Black (Figure 1.34), at that time pharmacologist at Smith Kline and French, who followed L. Popielski s concept of histamine involvement in the stimulation of this secretion, was awarded second Nobel... 

The preliminary studies of Gray et al. stimulated the English group at St. Thomas Hospital in London to determine whether the auspicious laboratory experiments can be extrapolated for human use in clinical radiotherapy. Churchill-Davidson, Sanger, and Thomlinson first reported their results on 8 patients in 1955 (C13, SI). The successful destruction of parts of tumors which received both OHP and X-irradiation as compared to X-irradiation alone inspired them to undertake a more extensive trial using curative radiation doses on whole tumors. Periodic reports of their work have appeared (C14, C15, S2). As of April 1963 they had treated 160 patients with advanced disease 38 (24%) of them had developed metas-tases outside the treated area and no less than 10 (6%) had developed a second primary tumor.. . . Although not uniform the overall response to treatment has been better than would have been expected from conventional radiotherapy, and in 15-20% of the cases has been quite dramatic. ... 

Department of Haematology, Louis Jenner Laboratories, St. Thomas Hospital and Medical School, London, England... 

Dr. Renee Arnold (ACT LLC, USA) Dr. David D. Christ (SNC Partners LLC, USA) Dr. Michael J. Curtis (Rayne Institute, St Thomas Hospital, UK) Dr. James H. Harwood (Pfizer, USA) Dr. Dale Johnson (Emiliem, USA) Dr. Mark Murcko, (Vertex, USA) Dr. Peter W. Swaan (University of Maryland, USA) Dr. David Wild (Indiana University, USA) Prof. William Welsh (Robert Wood Johnson Medical School University of Medicine Dentistry of New Jersey, USA) Prof. Tsuguchika Kaminuma (Tokyo Medical and Dental University, Japan) Dr. Maggie A.Z. Hupcey (PA Consulting, USA) Dr. Ana Szarfman (FDA, USA)... 

Beaty, T.H., Prenger, V.L., Virgil, D.G., Lewis, B., Kwiterovich, P.O., and Bachorik, P.S. (1992) A genetic model for control of hypertriglyceridemia and apolipoprotein B levels in the Johns Hopkins colony of St. Thomas Hospital rabbits. Genetics 132, 1095-1104. 

The era of the hospital began in the twelfth century when the sick were to be housed in separate buildings designed for medical care. Examples include St. Bartholomew s Hospital (London, AJ>. 1123) and St. Thomas Hospital (London, A.D. 1200). Both hospitals are in service today, having been refounded in the mid-1500s due to the dissolution of the monasteries in England in AI>. 1536. 

We are indebted to Andrew Lumsden and Cheryll Tickle for patiently teaching the microsurgical procedures described here. The both could have written the chapter better than the authors. S. Dietrich is supported by grants by the BBSRC and The Charitable Fund for Guy s and St. Thomas Hospitals, C. Lours by a Bourse d excellence regionale of the region Auvergne, France. 

Professor of Interventional Radiology, University of London, Guy s and St. Thomas Hospital School of Medicine, St. Thomas Hospital, London, SEl TEH, UK... 

Reported experience for the newer stent designs, such as the Flamingo and Ultraflex stents, is relatively hmited. Poyanli et al. (2001) reported good symptomatic relief and no procedure-related complications in 33 patients treated with the Flamingo stent (Poyanli et al. 2001). In a recent randomized prospective study at Guy s Hospital and St. Thomas Hospital, 37 patients were treated with Flamingo or covered Ultraflex stents. Both stents produced comparable improvements in dysphagia rehef and a similar low incidence of complications. 

By the mid nineteenth century the Registrar General had amassed a great deal of statistical information about occupational disease. Dr E. H. Greenhow of St Thomas Hospital showed from these figures that much of the chest disease in certain areas of the country was due to the inhalation of dust and fume at work. 

Department of Rheumatology, King s College and St. Thomas Hospitals Medical and Dental Schools, Guy s Hospital, London SEl 9RT, U.K. 

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