Spong, William

Texter J, Antalek B and Williams A J 1997 Reverse micelle to sponge phase transition J. Chem. Phys. 106 7869-72... 

Pettit, G.R. Butler, M.S. Williams, M.D. Filiatrault, M.J. Pettit, R.K. (1996) Isolation and structure of hemibastadinols 1 -3 from the Papua New Guinea marine sponge lanthella basta. J. Nat. Prod., 59,927-34. 

Williams, D.E. Lassota, P. Andersen, R.J. (1998) Motuporamines A-C, cytotoxic alkaloids isolated from the marine sponge. Xestospowg/aexjgwa. J. Org. Chem., 63,4838-41. 

Williams DE, Patrick BO, Behrisch HW, van Soest R, Roberge M, Andersen RJ (2005) Dominicin, a Cyclic Octapeptide, and Laughine, a Bromopyrrole Alkaloid, Isolated from the Caribbean Marine Sponge Eurypon laughlini. J Nat Prod 68 327... 

Linington RG, Williams DE, Tahir A, van Soest R, Andersen RJ (2003) Latonduines A and B, New Alkaloids Isolated from the Marine Sponge Stylissa carteri Structure Elucidation, Synthesis, and Biogenetic Implications. Org Lett 5 2735... 

Williams DH, Faulkner DJ (1996) A-Methylated Ageliferins from the Sponge Astrosclera willeyana from Pohnpei. Tetrahedron 52 5381... 

Williams DE, Roberge M, Van Soest R, Andersen RJ (2003) Spirastrellolide A, an Antimitotic Macrolide Isolated from the Caribbean Marine Sponge Spirastrella coccinea. J Am Chem Soc 125 5296... 

Pettit GR, Butler MS, Williams MD, Filiatrault MJ, Pettit RK (1996) Isolation and Structure of Hemibastadinols 1-3 from the Papua New Guinea Marine Sponge lanthella basta. J Nat Prod 59 927... 

Williams, D. H. and Faulkner, D. J., /V-Methylated ageliferins from the sponge Astrosclera willeyana from Pohnpei, Tetrahedron, 52, 5381, 1996. 

De Silva, E.D., Williams, D.E., Andersen, R.I, Klix, H., Holmes, C.EB. and Allen, T.M. 1992. Motuporin, a potent protein phosphatase inhibitor isolated from the Papua New Guinea sponge Theonella swinhoei Gray. Tetrahedron Lett 33 1561-1564. 

Spirastrellolide A [sponge] C52HS1CIO17 Comment bis-spiroketal, potent PP2A activity Williams etalP... 

Beman, V. S., Roll, D. M., Ireland, Chris M., Greenstein, M., Maiese, William M., Steinberg, D. A., (1993). A study on the mechanism of action of sceptrin, an antimicrobial agent isolated from the South Pacific sponge Agelas mauritiana. J. Antimicrob. Chemother. 32, 539-550. 

Linington, R. G., Williams, D. E., Tahir, A., Van Soest, R. W., Andersen, R. J., (2003). Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri Structure elucidation, synthesis, and biogenetic implications. Org. Lett. 5,2735-2738. 

Uludag, H., Friess, W., Williams, D., Porter, T., Timony, G., D Augusta, D., Blake, C., Palmer, R., Biron, B., and Wozney, J. (1999), rhBMP-collagen sponges as osteoinductive devices Effects of in vitro sponge characteristics and protein pi on in vivo rhBMP pharmacokinetics, Ann. N.Y. Acad. Sci. 875 369-378. 

Determination of the concentration of acid in human gastric juice waited upon the ability to collect a pure sample. Until such samples could be collected from fistulous subjects, some persons sampled their own gastric juice by means of a sponge attached to a string, and others analyzed vomitus. Sir Astley Cooper gave William Prout, the man who established the presence of hydrochloric acid in the gastric contents of animals, fluid ejected from the human stomach in severe cases of dyspepsia. Prout found muriatic acid in a free or unsaturated state in concentrations of 4.28,4.63, and 5.13 grains per pint. ... 

Superstolide A 3, isolated from the New Caledonian sponge Neosiphonia superstes, shows interesting cytotoxicity against malignant cell lines at 4 ng/mL concentration. The key transformation in the synthesis of 3 described J. Am. Chem. Soc. 2008,130, 2722) by William R. Roush of Scripps Florida was the transannular Diels-Alder cyclization of 2, which established, in one step with high diastereocontrol, both the cis decalin and the macrolactone of 3. 

Williams, D.E., Roberge, M., Van Soest, R., and Andersen, R.J. (2003) Spirastrelolide A, an antimitotic macrolide isolated from the Caribbean marine sponge Spirastrella coccinea. J. Am. Chem. Soc., 125, 5296-5297. 

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