Sphingosine l-phosphate

Sphingosine-l-phosphate Receptor 1 and Egress from Lymph Nodes... 

Sphingosine kinase expression incieases intracellular sphingosine-l-phosphate and promotes ceU growth and survival. J. Cell. Biol. 147 545-558. 

Mandala, S.M., 2001, Sphingosine l-phosphate phosphatases. Prostaglandins Lipid Mediators 64 143-156. 

Constable, P. D., Riley, R. T., Waggoner, A. L., Hsiao, S. H., Foreman, J. H., Tumbleson, M. E., and Haschek, W. M. (2005). "Serum sphingosine-l-phosphate and sphinganine-l-phos-phate are elevated in horses exposed to fumonisin Bi" AOAC International Midwest Section Final Program, pp. 63-64. 

Cyster, J. G. (2005). Chemokines, sphingosine-l-phosphate, and cell migration in secondary lymphoid organs. Annu. Rev. Immunol. 23,127-159. 

Sanchez, T., Skoura, A., Wu, M. T., Casserly, B., Harrington, E. O., and Hla, T. (2007). Induction of vascular permeability by the sphingosine-l-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arterioscler. Thromb. Vase. Biol. 27(6), 1312-1318. 

Spiegel, S. and Milstien, S. (2003). Sphingosine-l-phosphate An enigmatic signalling lipid. Nat. Rev. Mol. Cell Biol. 4(5), 397M07. 

Stunff, H. L., Milstien, S., and Spiegel, S. (2004). Generation and metabolism of bioactive sphingosine-l-phosphate. J. Cell Biochem. 92(5), 882-899. 

Sphingosine-l-phosphate (= SIP) Universal likely signaller in S1P-R EDG-1 agonist... 

Spiegel S, Milstien S (2003) Sphingosine-l-phosphate an enigmatic signalling Upid. Nat Rev Mol Cell Biol 4 397-107... 

Van Brooklyn JR, Graler MH, Bernhardt G, Hobson JP, Lipp M, Spiegel S (2000) Sphingosine-l-phosphate is a ligand for the G protein-coupled receptor EDG-6. Blood 95 2624—2629... 

Yu N, Lariosa-Wilhngham KD, Lin FF, Webb M, Rao TS (2004) Characterization of lysophosphatidic acid and sphingosine- l-phosphate-mediated signal transduction in rat cortical ohgodendrocytes. Glia 45 17-27... 

Clemens, J. J., Davis, M. D., Lynch, K. R., Macdonald, T.L. Synthesis of para-alkyl aryl amide analogues of sphingosine-l-phosphate discovery of potent SIP receptor agonists. Bioorg Med Chem Lett 13 (2003) 3401-3404. 

Harada, J., Foley, M., Moskowitz, M. A., Waeber, C. Sphingosine-l-phosphate induces proliferation and morphological changes of neural progenitor cells. J Neurochem 88... 

S., Spiegel, S. Transactivation of sphingosine-l-phosphate receptors by FcepsilonRI... 

Kupperman, E., An, S., Osborne, N., Waldron, S., Stainier, D. Y. A sphingosine-l-phosphate receptor regulates cell migration during vertebrate heart development. Nature 406 (2000) 192-195. 

LaMontagne, K., Littlewood-Evans, A., Schnell, C., O Reilly, T., Wyder, L., Sanchez, T., Probst, B., Butler, J., Wood, A., Liau, G., Billy, E., Theuer, A., Hla, T., Wood, J. Antagonism of sphingosine-l-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization. Cancer Res 66 (2006) 221-231. 

Sugimoto, N., Takuwa, N., Okamoto, H., Sakurada, S., Takuwa, Y. Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-l-phosphate receptor isoform. Mol Cell Biol 23 (2003) 1534-1545. 

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