Specific storage

Each blood component has specific storage requirements in terms of optimal temperature, additives, expiration, and storage containers. Red blood cells (RBC) from whole blood, provided in 200 mL units, have an expiration of 42 days. Fro2en, deglycerolized RBC, in 170 mL containers, and washed red cells, in 200 mL containers, both expire 24 hours after thawing and washing, respectively leukocyte-reduced RBC, in 200 mL containers, are viable for 24 hours. 

When animals are fed experimental diets lacking copper or zinc, their copper or zinc status rapidly declines, suggesting that there is not a storage pool of these metals. Thus, while the small, cysteine-rich protein metallothionein (see below) can avidly bind zinc and copper, this may reflect its role in detoxification rather than as a specific storage form. This is reflected by the fact that metallothionein genes are typically expressed at a basal level, but their transcription is strongly induced by heavy metal load. 

Chemicals, reagent and solutions should be labeled to indicate identity, expiry and specific storage instructions. 

Egalhaaf, A., Coelln, K., Schmitz, B Buck, M Wink, M. and Schneider, D. (1990). Organ specific storage of dietary pyrrolizidine alkaloids in the arctiid moth Creatonotus transiens. Zeitschrift fur Naturforschung 45c 172-177. 

Whether specific storage forms are involved for the trace metals is debatable.107 Such a role has been alluded to for the non-exchangeable protein complexes in serum, i.e. caeruloplasmin for Cu, and a2-macroglobulin for Zn, and to metallothionein protein (Chapter 20.2). However, it has also been argued that there are sufficient deposits within body tissues to provide at least short-term storage of the minute quantities that are required. 

Storage Under Nonspecific Conditions Where no specific storage directions or limitations are provided in the individual monograph, the conditions of storage and distribution include protection from moisture, freezing, and excessive heat. Containers should be stored in secure areas when not in use to reduce the possibility of tampering. 

Installed/Not Installed Availability of Spares Modified Specifications Storage of Spares Catalog of Spares... 

There is no specific storage organ for ascorbate apart from leukocytes (which account for only 10% of total blood ascorbate), the only tissues showing a significant concentration of the vitamin are the adrenal and pituitary glands. Although the concentration of ascorbate in muscle is relatively low, skeletal muscle contains much of the body pool of 5 to 8.5 mmol (900 to 1,500 mg) of ascorbate. 

This slope permits one to determine the drop in titer (or activity) after a specific storage period and to evaluate whether the remaining activity of the product at that time is sufficient for the product to be used. 

Ensure that the advice provided is consistent with the physical and chemical properties in Section 9 - Physical and chemical properties of the SDS. If relevant, provide advice on specific storage requirements including ... 

In a confined aquifer, the quantity corresponding to specific yield is called storativity, 5, and is typically much smaller than Sy. Storativity is a function of the compressibility of water and aquifer material and is proportional to aquifer thickness. A related term is specific storage, Ss, which is storativity divided by aquifer thickness. Storativity increases as thickness of the aquifer increases, whereas specific yield is not a function of aquifer thickness. Removal of large volumes of water from confined aquifers can result in measurable ground subsidence. 

To ensure the completed prescription is handed out to the correct person (patient/ representative) including items with specific storage requirements (for example, fridge items or items kept in the controlled drugs cupboard) (audit question 2). 

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