Sodium thioglycollate

Sodium thioglycolate [367-51-1] M 114.1. Crystd from 60% EtOH (charcoal). Hygroscopic. 

To 50 cc of a carefully purified aqueous solution of the sodium salt of N(7-chloromercuri-)3-methoxy-propyl)-d-a-camphoramic acid containing 40 mg of mercury per cc is added 10 cc of a solution containing 1.14 g (1 mol equivalent) of sodium thioglycollate and the mixture is then evaporated to dryness at room temperature and reduced pressure in the presence of a desiccant. The product is an amorphous white powder which decomposes at 156° to 158°C (uncorr,), and which was found on analysis to have a mercury content of 33.0%, according to U.S. Patent 2,576,349. 

Bis-[3,4-b, 4,3-e]thiophenylpyrazines can also be prepared from 2,6-dichloro-3,5-dicyanopyrazine and sodium thioglycolate, but in lower yields than for the corresponding pyridine derivatives <2004T275>. 

Halogens, iodine, chlorine, glutaraldehyde Sodium thioglycolate 5 g/l... 

Vitamins—fat soluble Whole amounts of Sorbita was mixed with PN-Twin no. 2 (2.2 L) Sodium citrate, sodium pyrosulfite, sodium thioglycollate, HCO-60, benzyl alcohol, polysorbate 80 Aminoethylsulfonic acid, sesame oil, soybean lecithin, D-sorbitol, concentrated glycerin 1,157.1 5.1... 

Streptomycin was inactivated by reducing and oxidizing agents. The bacteriostatic-activity of this antibiotic for Escherichia coli was reduced in the presence of cysteine, sodium thioglycolate, stannous chloride, sodium bisulfite, sodium hydrosulfide, sodium formate and sodium thiosulfate. Cysteine was the most active. Denkelwater, Cook and Tishler found that the cysteine inactivation of streptomycin could be reversed by iodine presumably cystine was formed during this process. Rake and Donovick inactivated streptomycin with semi-carbazide hydrochloride in order to test the sterility of concentrated streptomycin solutions. The inactivation of streptomycin by compounds containing sulfhydryl groups has been discussed by Cavallito. ... 

Several factors influence the antimicrobial activity of silver salts [19]. Silver has a marked tendency to adsorb to surfaces and bactericidal activity is reduced in the presence of phosphates, chlorides, sulphides and hard water. Activity is increased as the temperature is raised (Q,o = 1.6, that is, a 1.6-fold increase in activity per 10°C rise in temperature) and is pH-dependent, increasing with increasing pH [19, 20]. Sodium thioglycol-late has been recommended as a suitable neutralizing agent for use in... 

Antimony Sodium Thioglycollate, [t5-Oxo-F3,2-oxathioxtibalan-2-yl)thin]Gt etic acid sodium salt mercapio-aeetic acid antimony derivative. sodium saJt antimony sodium ihiotfcetaie. C4H4Na04 aSb mol wt 324.96. C 14 78%-H 1.24%, Na 7-08%, O 19.70%, S 19,73% Sb 37.47%. Prepn... 

For GAnB enumeration, a medium was prepared under anaerobic conditions with the following composition (per liter) glucose, 5.0 g peptone, 4.0 g yeast extract, 1.0 g resazurin 4 ml (0.025% m/v), at pH 7.6. After preparation, the medium was distributed into 9 ml flasks and sterilized in an autoclave at 121 °C for 20 min. Then, sodium thioglycolate (12.4 g/I) was added, as previously described. 

Camphoric acid on condensation with ammonia and subsequent treatment with allyl isocyanate aflfords an intermediate which on reaction with mercuric acetate in methanol gives rise to the corresponding mercury derivative as acetate. This on treatment with sodium chloride followed by sodium thioglycollate in aqueous NaOH solution yields the offieial eompound which may be obtained either by evaporation or by preeipitation with an appropriate solvent. 

---