Sodium methyl Cellosolv

Discussion. Hydroxyl groups present in carbohydrates can be readily acetylated by acetic (ethanoic) anhydride in ethyl acetate containing some perchloric acid. This reaction can be used as a basis for determining the number of hydroxyl groups in the carbohydrate molecule by carrying out the reaction with excess acetic anhydride followed by titration of the excess using sodium hydroxide in methyl cellosolve. 

Redox titrants (mainly in acetic acid) are bromine, iodine monochloride, chlorine dioxide, iodine (for Karl Fischer reagent based on a methanolic solution of iodine and S02 with pyridine, and the alternatives, methyl-Cellosolve instead of methanol, or sodium acetate instead of pyridine (see pp. 204-205), and other oxidants, mostly compounds of metals of high valency such as potassium permanganate, chromic acid, lead(IV) or mercury(II) acetate or cerium(IV) salts reductants include sodium dithionate, pyrocatechol and oxalic acid, and compounds of metals at low valency such as iron(II) perchlorate, tin(II) chloride, vanadyl acetate, arsenic(IV) or titanium(III) chloride and chromium(II) chloride. 

Methyl cellosolve, see Methyl cellosolve acetate Methyl chloride, see Dalapon-sodium. 

Pew found that the residue, mainly lignin, from unground wood digested by cellulytic enzymes was insoluble in IN sodium hydroxide while the residue from finely ground wood was freely soluble 26). Also, spruce periodate lignin, normally insoluble in methyl cellosolve and in 0. N... 

The solvent used in the determination of rotations appears in parentheses. Key to solvents (a) acetone (c) chloroform (d) dioxane (de) 95% ethanol (e) ethanol (m) methanol (mC) methyl Cellosolve (n) 8% sodium hydroxide (Nn) N sodium hydroxide (p) pyridine (s) 1% sulfuric acid (w) water. The temperature range is from 13 to 31°. b References 278 to 308 appear in a separate list starting on page 380. Italicized references are for infrared absorption spectra all others refer to ultraviolet absorption spectra. 

PVPyrH Poly-4-vinylpyridine (PVPyr) prepared by conventional persulfate catalyzed polymerization was dissolved in ethyl alcohol or methyl Cellosolve (2 to 3% solution) for application to polyester film substances. These films adsorb heparin from solutions of sodium heparin to produce anticoagulant surfaces (PVPyrH). Films were painted on, or spread by knife coating. 

For an isolated lignin, a 20-mg sample is dissolved in 50ml of ethanol or methyl cellosolve. To 2 ml of this solution are added the same amounts of quinone monochlorimide and sodium hydroxide as were used in the above procedure. The solution is allowed to stand for 1 h at room temperature. Two ml of the solution is diluted to 25 ml with methyl cellosolve or ethanol and the absorption spectrum (/max 640 nm) is recorded spectrophotometrically. 

An enantioselective synthesis of TIQ-1-carboxylic acids 91a,b has recently been reported (279). Hydrolysis of the optically active methyl ether enantiomer of hydantoin 103 was accomplished by 20% sodium hydroxide in refluxing methyl cellosolve and led to the dimethyl ether analog of 91a, which was used to establish the absolute configuration of the products. Amino acids 91a,b have also been prepared by chemical resolution of the N,0-benzylated acid 108 with optically active 1-phenylethylamines. Catalytic debenzylation of enantiomer 109a gave... 

Walden inversion, at C3, of methyl 2-acetamido-2-deoxy-4-0-methyl-3,6-di-O-methylsulfonyl-a-D-glucoside took place on heating it with sodium acetate in 2-methoxyethanol (methyl Cellosolve) solution the product afforded, after acetylation, a sirupy methyl 2-acetamido-3,6-di-0-acetyl-2-deoxy-4-0-methyl-a-D-alloside. Removal of the 0-acetyl groups, followed by methylation, gave the same 3,4,6-trimethyl ether previously reported. 

A mixture of 20 g 1,2,3,4-tetrahydroquinoline, 25 mL methyl Cellosolve, 2 g potassium iodide, and 28.1 g 2-bromoethylphthalimide was heated overnight on a steam bath. The solvent was evaporated in vacuo from the dark reaction product, and the residue was dissolved in dilute hydrochloric acid, filtered from insoluble material, and then made alkaline with a sodium carbonate solution. The resulting 2-(l, 2, 3, 4 -tetrahydroquinolino)-ethylphthalimide that recrystallized from aqueous alcohol (m.p. 131-133°C), was suspended in 50 mL absolute alcohol, and 2.4 g 85% hydrazine hydrate was added. After the mixture was warmed gently for 5 h, an excess of dilute hydrochloric acid was added, and the mixture was filtered after standing for 1 h. An excess of 12.5 N NaOH was added to the filtrate, and a small amount of oily 2-(l, 2, 3, 4 -tetrahydroquino-lino)-ethylamine was taken up in methyl acetate. 

M phosphate, pH 7.4, + 1 M sodium chloride, 20% methyl Cellosolve, and 1% SDS detection, fluorescence, o-phthalaldehyde method (J. Benson andP. Hare, Proc. Natl. Acad. Sci. USA,... 

The sample (200/il in water) is mixed with 100/il of benzoin solution (4 mM in methyl cellosolve), and 100 fi of an aqueous solution containing 0.1 M 2-mercapto-ethanol and 0.2 M sodium sulphite and 200 fi of 2.0 M potassium hydroxide. The mixture is heated in a boiling water bath for 5 min, then cooled on ice, and 200 [il of a 1 1 mixture of 2 M HCI 0.5 M Tris/HCI buffer, pH 9.2 is added. Aliquots (100/il) are used for chromatographic separations. 2-Mercaptoethanol stabilizes the resultimidazole derivatives and sodium sulphite suppresses background fluorescence. 

Preparation by partial alkylation of 2,4-dihy-droxy-5-methylbenzophenone with octyl chloride in the presence of sodium bicarbonate and potassium iodide in 1-methyl-pyrroUdone for 2 h at 150° (91%) [867] or in refluxing methyl cellosolve [887]. 

Add 10 ml of a 01M sodium acetate-acetic acid buffer, pH 4-6. Adjust the volume to 100 ml using a mixture of equal parts of methyl cellosolve and distilled water. Add 0 2 g of lanthanum chloranilate, shake the flask immediately and then allow to stand for thirty minutes, shaking at frequent intervals. Filter or centrifuge to give a clear solution and measure the extinction in a 1-cm cell at 530 m/j, against a blank prepared in the same way. For greater sensitivity (in the range 0 5 to 4 0 jug per ml), the extinction should be measured at 330 m//. 

The following procedure has been used by Hartmann (1963) to prepare alcohol-free C-diazomethane in about 60-65% yield. N-Methyl-C -N-nitroso-p-toluenesulfonamide (22 mg, 0.103 mmole, 0.1 mC of C " ) was dissolved in 1 ml of anhydrous, peroxide-free diethyl ether in a 5-ml distilling flask fitted with a gas inlet tube. The side arm was bent vertically downward near the top and connected through a two-holed rubber stopper to a 10-ml Erlenmeyer flask. A tube from the second hole led to the back of the hood. The latter flask was cooled in a Dry-Ice-Cellosolve bath. With the reaction flask at room temperature, 1 ml of a solution of 10 mg of sodium metal in dry n-octyl alcohol was added all at once. The gas inlet tube was immediately connected and a slow stream of dry nitrogen was passed through the system. The temperature of the mixture was then raised to 70°C in an oil bath and the C-diazomethane was flushed into the cooled collection flask for about 15 min. A further 1 ml of ether was then added through the gas inlet tube and collection was continued until the distillation of the ether was complete. Use of C-dia-zomethane represents the most general method for the introduction of radioactivity into a haloketone. 

Properties White, crystalline solid. Fp 70C, bp 265C, d 1.048 (20/4C), viscosity 3.47 centistokes (0C), 1.54 centistokes (120C), refr index 1.4859 (75C), flash p 275F (135C) (COC). Soluble in methanol, ethanol, isopropanol, Cellosolve (12C), naphtha, benzene, methyl ethyl ketone, and linseed oil insoluble in water and 10% sodium hydroxide. Combustible. 

Chem. Descrip. Sodium N-methyl-N-cocoyl taurate lor)ic Nature Anionic Chem. Analysis 5,0% max, free faty acid CAS 61791-42-2 61788-47-4 EINECS/ELINCS 235-802-1 Uses Surfactant for bath prods, body wash, facial cleanser, liq, soap, shampoo Features Exc, sol, outstanding detergency, wetting props, stable in high electrolyte systems, mild acids mild to hair, skin Properties Cl, to cloudy liq, APHA color (15% in 20% butyl cellosolve) 200 max, ... 

---