Sodium glycolate analysis

Chem. Analysis 0.5% free coconut fatty acid 0.7% sodium glycolate 0.5% free amidoamine... 

The formation of acetals with methanol, ethanol, or ethylene glycol in the presence of an acid catalyst such as hydrogen chloride or ben2enesulfonic acid is straightforward. Sodium bisulfite and hydroxjlamine form adducts with cinnamaldehyde that are used in typical quantitative analysis protocols. 

Ethylene glycol has been used instead of water as solvent in the deposition of CdS films from cadmium acetate and sodium sulfide precursors. The films were amorphous and showed some excess cadmium (Cd/S atomic percentage ratio was 52.3/47.7) in EDX analysis.79... 

Many substances can serve as the stationary phase for gas chromatographic separations of methyl esters in most cases polyester, polyether, or silicone greases are used. Percival (18) has investigated the composition of polyesters by methanolysis with sodium methyl oxide. The dimethyl esters of the dicarboxylic acids present in the composition and free glycols are formed and subsequently are separated at temperatures between 110° and 180° C. on a column of GE silicone SF-96 and Fluoropak 80. It should be possible to adapt this method to the analysis of polyesters used as plasticizers. 

A fiber optic probe was used by Blanco et al. for analysis of spasmoctyl samples with the active compound otilonium bromide and cellulose, maize starch, sodium starch glycolate, and glyceryl palmitostearate as excipients. Another study from this group covered the identification, qualification of the substance, and the quantification of the active component. A library search with a comparison to the near-infrared spectra of 163 pharmaceuticals was involved. An on-line monitoring for the determination of the endpoint of polymorph conversions in pharmaceutical processes was recently described further investigations into this field were published and are noted previously. ... 

The preparation of the salt (95) has been improved by using phosphorus trichloride at room temperature instead of the pentachloride at — 70 °C. The spirophosphorane (96) with ethylene glycol and sodium methoxide gave the tris(ethylenedioxy)phosphate (97). Attempts to prepare the six-membered-ring analogue failed, A"-Ray analysis of the salt (98) confirmed the octahedral arrangement of oxygens around phosphorus. 

Analysis of the coefficients indicates that the drug is relatively unstable when formulated. Formulations containing cellulose are less stable than those with lactose and sodium starch glycolate has a deleterious effect on stability compared with starch. There appears to be no difference between the lubricants and the binders tested and the presence of colloidal silica has no effect on the stability. 

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