D-Tartrate sodium

Solutions of cobalt(II) sulfate heptahydrate (28.1 g. 0.1 mol) and sodium d-tartrate (23.0 g. 0.1 mol), each dissolved in 50 ml. of water at 65°, are mixed and stirred. After about a minute purple-red cobalt (II) d-tartrate separates and the mixture is maintained at 65° for 15 minutes, then cooled in ice, and filtered. The precipitate is washed with 50 ml. of ice water, then acetone, and air-dried. Ethylenediamine (20.4 ml. of 88.6% w/v 0.3 mol) is placed in a 500-ml. filter flask fitted with a rubber stopper and a... 

The purified commercial di-n-butyl d-tartrate, m.p. 22°, may be used. It may be prepared by using the procedure described under i o-propyl lactate (Section 111,102). Place a mixture of 75 g. of d-tartaric acid, 10 g. of Zeo-Karb 225/H, 110 g. (136 ml.) of redistilled n-butyl alcohol and 150 ml. of sodium-dried benzene in a 1-litre three-necked flask equipped with a mercury-sealed stirrer, a double surface condenser and an automatic water separator (see Fig. Ill, 126,1). Reflux the mixture with stirring for 10 hours about 21 ml. of water collect in the water separator. FUter off the ion-exchange resin at the pump and wash it with two 30-40 ml. portions of hot benzene. Wash the combined filtrate and washings with two 75 ml. portions of saturated sodium bicarbonate solution, followed by lOu ml. of water, and dry over anhydrous magnesium sulphate. Remove the benzene by distillation under reduced pressure (water pump) and finally distil the residue. Collect the di-n-butyl d-tartrate at 150°/1 5 mm. The yield is 90 g. 

Sodium R-tartrate (2H2O) [6106-24-7] M 230.1, m 120°(loses H2O), d 1.82. Crystd from warm dilute aqueous NaOH by cooling. 

Figure 5.45 Cationic gemini amphiphiles having chiral counterions. TEM images of representative twisted ribbons formed by 16-2-16 tartrate (49 + 50) at 0.1% in water for various values of enantiomeric excess (a) 0 (racemate) (b) 0.5 (c) 1 (pure L) (d) 1 (pure L) in presence of 1 eq sodium L-tartrate. Bar = 100 nm. Reprinted with permission from Ref. 165. Copyright 1999 by Macmillan Magazines.

D. Tris[(2-peiiluorohexyl)ethyl]tin hydride (Note 7). A 1-L, three-necked flask and a stirring bar are dried in an oven. The fluorous tin bromide (13.8 g, 11.1 mmol) is dissolved in dry ether (275 mL) and transferred to the dried three-necked flask equipped with a thermometer, stirring bar, and an outlet to argon. The solution is cooled to O C. AIM solution of iithium aluminum hydride (LAH) in ether (11.1 mL, 11.1 mmol) is added dropwise over 45 min to the solution. The addition rate is adjusted to maintain a temperature between 0° and 1°C. The reaction mixture is stirred for 6 hr at 0°C. Water (75 mL) is slowly added (initially dropwise) with stirring to the ice-cold mixture. Sodium potassium tartrate (20%) (250 mL) is added and the mixture is transferred to a 1-L separatory funnel. The ethereal layer is separated and the aqueous layer is extracted three times with ether (3 x 100 mL). The combined extracts are dried with magnesium sulfate and vacuum filtered into a 1-L, round-bottomed flask. The solvent is evaporated under reduced pressure. The cmde product is distilled under a reduced pressure of 0.02 mm at 133-140°C to provide 11.3 g (9.69 mmol, 87%) of the pure product as an oil (Notes 8 and 9). 

Dextro iodide. The chloride d-tartrate is dissolved in 30 ml. of hot water concentrated ammonia solution (0.5 ml.) is then added, followed with stirring by 35 g. of sodium iodide dissolved in 15 ml. of hot water. The iodide crystallizes as reddish-orange needles on cooling. Complete crystallization is effected by cooling in ice for 15 minutes. After filtration the crystals are sucked very dry and washed with ice-cold 30% sodium iodide (20 ml.) to remove tartrate and then with ethanol and acetone. The yield of the air-dried product, [q ]d = +89°, is 24 g. (35%). Anal. Calcd. for [Co(en)3]I3-H20 C, 11.26 H, 4.11. Found C, 11.23 H, 4.17. 

In 1951, it became possible to determine whether Rosanoff s guess was right. Ordinary X-ray crystallography cannot distinguish between a d and a l isomer, but by use of a special technique, Bijvoet was able to examine sodium rubidium tartrate and found that Rosanoff had made the correct choice. It was perhaps historically fitting that the first true absolute configuration should have been determined on a salt of tartaric acid, since Pasteur made his great discoveries on another salt of this acid. 

Tables IV-VIII describe the Pfeiffer Effect on the D.L-fNi(o-phen)o] with ( +) -tartaric acid, sodium hydrogen (+) tartrate, the diethyl-2-methoxy-...

THE PFEIFFER EFFECT WITH SODIUM HYDROGEN (+)D TARTRATE-OBSERVED OPTICAL ROTATION IN DEGREES... 

Analogous phenomena are met with in systems constituted of two salts and water in which the formation of double salts can take place. Thus, for example, if (i-sodium potassium tartrate is heated to above 55°> apparent partial fusion occurs, and the two single salts, d -sodium tartrate and f-potassium tartrate, are deposited, the change which occurs being represented by the equation... 

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