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Small-molecule , generally drugs

While LIF monitoring is established in other manufacturing industries, it is relatively new within the pharmaceutical industry. The application of real-time intrinsic LIF for the manufacture of pharmaceuticals in general can be broken in to three areas (i) classic (small molecule) final drug product manufacturing (ii) biopharmaceutical prodnct manufacturing and (iii) factory operational applications. [Pg.349]

Homogeneous EIA lend themselves better to dose-response curve linearization than solid-phase EIA. This type of EIA is generally used for the determination of concentrations of small molecules (haptens, drugs). The major supplier of this type of EIA kits (Syva Co.) recommends the plotting of the response variable ( EMIT Units ) vs the log of the concentration or the presentation of the results on special non-linear graph paper provided by them, which is, in fact, logit-log paper. [Pg.413]

The second main area of application for cellulose-based polymers is the encapsulation of active small molecules for drug delivery [40,48]. As briefly mentioned above, different celluloses are differently suited for this purpose. Generally, microcrystalline cellulose is the preferred material for this kind of application [63]. As a matter of fact, most applications in this field exploit bacterial cellulose. [Pg.135]

Separation media, with bimodal chemistry, are generally designed for the complete separation of complex samples, such as blood plasma serum, that typically contain molecules differing in properties such as size, charge, and polarity. The major principle of bifunctional separation relies on the pore size and functional difference in the media. For example, a polymer bead with hydrophilic large pores and hydrophobic small pores will not interact with and retain large molecules such as proteins, but will interact with and retain small molecules such as drugs and metabolites. [Pg.11]


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See also in sourсe #XX -- [ Pg.615 ]




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Drug molecules

Drugs, general

Small-molecule drugs

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