Silicon containing compounds exposure

Hydrocarbons what s in a name Exposure to organic solvents Nephrotoxicity of organic solvents Silicon containing compounds ... 

Silicon occurrence, uses and essential chemistry Exposure to silicon containing compounds Nephrotoxicity of silicon containing compounds Pesticides ... 

Knowledge regarding renal injury and the development of anti-neutrophil cytoplasmic antibody (ANCA) positivity associated with silica exposure is rudimentary being hmited to epidemiological observations. Moreover, information about the health significance of the occupational exposure to other silicon containing compounds apart from silica and crystalline sihcates is lacking. 

A survey of the Hterature [28, 55-62, 66, 67, 69-74] indicates that the most frequent exposure to silicon involves exposure to silica and siUcates mainly in their crystalline forms. Health risks associated with the exposure to other silicon containing compounds were reported in the mortality study of 16.661 man-made mineral fiber workers employed during 1945 to 1963 at one of 17 U.S. manufacturing plants [70]. Fiber exposure... 

Much less is known about renal injury and silicon exposure. A number of observations of the past few years have suggested a primary or secondary role for substances such as silicon-containing compounds in the development of ANCA (anti-neutrophU cytoplasmic antibodies)-associated rapidly progressive glomerulonephritis or Wegener s granulomatosis (Nuyts et al. 1995, De Broe et al. 1996). 

Tab. 3.4 Exposure limits of silicon containing compounds as recommended by the NIOSH and ACCIH (NIOSH, 2002)...

Exposure limits are mainly concerned with concentrations of silicon-containing compounds in air particles in industrial settings. Exposure limits recommended by the National Institute for Occupational Safety and Health (NIOSH) and the American Conference of Governmental Industrial Hygienists (ACGIH) are presented in Table 3.4. 

Pellistor sensors can be rapidly poisoned by exposure to contaminants such as silicones, tetraethyl-lead, phosphorus containing compounds and high concentrations of H2S, and they can be damaged by exposure to high concentrations of combustible gas. They can also simply lose sensitivity slowly over time, which is why it is so important to regularly test their response to known concentration calibration gas. 

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