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Signal transduction adaptor proteins

On the cytoplasmic side, a multitude of proteins have been reported to be implicated in integrin signal transduction. These proteins either interact directly with the cytoplasmic tails of the a and fi subunits or they are recruited by adaptor proteins into focal... [Pg.413]

Grb-2 facilitates the transduction of an extracellular stimulus to an intracellular signaling pathway, (b) The adaptor protein PSD-95 associates through one of its three PDZ domains with the N-methyl-D-aspartic acid (NMDA) receptor. Another PDZ domain associates with a PDZ domain from neuronal nitric oxide synthase (nNOS). Through its interaction with PSD-95, nNOS is localized to the NMDA receptor. Stimulation by glutamate induces an influx of calcium, which activates nNOS, resulting in the production of nitric oxide. [Pg.16]

The adaptor protein Grb2 of Ras signal transduction (see 8.5 and Chapter 9)... [Pg.297]

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See also in sourсe #XX -- [ Pg.394 , Pg.397 ]



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Adaptor proteins

Adaptors

Protein signals

Protein transduction

Signal transduction

Signaling protein

Signaling transduction

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