Side effects dangerous

The purpose of this book is to provide the user with concise reference information on various legal psychotropic materials. These include plant materials in their crude hebal form, and chemicals either synthesized or extracted from natural minerals. For each item there is a brief description of the material, the method of preparation, dosage and use, analysis of active constituents, effects, contraindications (side effects, dangers, etc.), and names of commercial suppliers. The latter are given as letter codes. The corresponding names and addresses are to be found in the section titled "Suppliers." Because of increasing interest in horticulture of psychotropic plants, sources of seeds and live plants are also given. 

All decisions involve tradeoffs. Does the benefit of increased food product ion outweigh possible health risks of a pesticide Do the beneficial effects of a new drug outweigh a potentially dangerous side effect in a small fraction of users The answers are rarely obvious, but we should at least try to base our responses on facts. 

IhRNAs have also been used to induce an anti-HIV-1 RNAi response (Barichievy et al. 2007 Konstantinova et al. 2006, 2007 Liu et al. 2007). These IhRNAs can be processed into multiple effective siRNAs, thus preventing the chance of viral escape. Although IhRNA have been shown to effectively inhibit HIV-1 replication, there is currently no data on their ability to prevent viral escape. The use of multiple siRNAs or IhRNAs should take into account the increased danger of side effects due to interference with cellular miRNA processing and function. 

Discuss rare but dangerous side effects which may also occur. 

A dietary supplement may be safe when taken in the recommended doses but may become dangerous in higher doses. However, patients may develop side effects even when ingesting recommended doses. Adverse reactions may be due to allergic reactions, dietary supplements containing toxic substances, mis-identification of plant, mislabeling of plant, natural toxic substances such as pyrrolizidine alkaloids in comfrey, unnatural toxic substances such as heavy metals, or pesticides. 

Side effects associated with this type of diet pill often occur because, in causing the body to burn more calories, the pills speed up many body processes—possibly to a level that becomes dangerous. Examples are increased blood pressure and heart rate, which can lead to heart problems over time. Other side effects include nervousness and insomnia. 

Amphetamines are very effective for weight loss but their use is limited by serious side effects and the potential for abuse. Therefore, amphetamine is still FDA approved for other diseases but is no longer permitted for weight loss. Many drugs that are similar to amphetamine have been formulated in an attempt to promote weight loss without causing addiction and dangerous side effects. 

Sibutramine use also carries the risk of side effects, which include elevated blood pressure, increased heart rate, dry mouth, nausea, and dizziness. Abuse of sibutramine can cause dilated pupils, excessive bleeding or bruising, tremor, and anxiety. As with all prescription drugs, it is essential to use sibutramine according a doctor s instructions. The alternative is the possibility of unpleasant side effects and dangerous outcomes. 

A predictably dangerous side effect of nadolol that constitutes a contraindication to its clinical use in susceptible patients is the induction of... 

Problems associated with these drugs include troublesome and potentially dangerous side effects, including extrapyramidal reactions, hypersensitivity reactions with possible liver dysfunction, marrow aplasia, and excessive sedation. 

Reactivity A substance s susceptibility to undergoing a chemical reaction or change that may result in dangerous side effects, such as explosion, burning, and corrosive or toxic emissions. 

Since she is in considerable pain the best alternative for this otherwise physically intact woman is an operation of her knees. In the meantime a supportive knee bandage can help relieve her pain in some way. She must tell her doctor that she is taking NSAIDs and be properly informed of the side effects and how to use the drug. The drug should only be used for short periods and in low doses because of the considerable danger of different side effects. 

The control of dangerous reactions to components in foods is not as widely conducted as is the monitoring of side effects caused by pharmaceuticals. This problem results mainly from the complexity of food matrices, and from the limited possibilities for attributing specific effects to particular food components. 

Augmenting antidepressants with lithium has repeatedly been shown to be effective. But lithium is a difficult medication to take. It is very dangerous in overdose and can quickly reach toxic levels due to fluid loss from diarrhea, profuse sweating, or high fevers. Even at treatment levels, lithium can produce unpleasant side effects such as dizziness, frequent urination, and tremors. Despite all its problems, lithium... 

The most talked about and concerning side effect of clozapine is a potentially dangerous reduction in the number of white blood cells. This side effect, called agranulocytosis, occurs in about 1% of patients treated with clozapine. Although we... 

The side effects of barbiturates include sedation, poor physical coordination, and impaired mental performance. They also potentiate the intoxicating effects of alcohol. Barbiturates can be extremely dangerous in overdose, causing anesthesia, coma, and even death. In addition, barbiturates can cause dangerous suppression of breathing in patients with sleep apnea or other respiratory disorders. With repeated use over just a few weeks, physical dependence and tolerance to their effects can develop, leading to increasing doses to maintain the desired therapeutic effect. If a... 

Side effects of benzodiazepines include sedation, dizziness, poor coordination, and, at higher doses, amnesia. Benzodiazepines also increase the effects of alcohol therefore, alcohol use should be avoided or markedly curtailed. Benzodiazepines can also exacerbate the breathing problems of patients with sleep apnea and other respiratory disorders such as emphysema. Like the barbiturates, long-term use of benzodiazepines can lead to physical dependence, and abrupt discontinuation can produce an unpleasant, or even dangerous, withdrawal syndrome. 

Like the MAOIs, TCAs are hindered by a delayed onset of action that can be especially intolerable for those with frequent and severe panic attacks. When starting treatment, TCAs, like SSRIs, may also produce a transient nervousness that is especially uncomfortable for those with panic disorder. When this occurs, the starting dose should be reduced by half, and the pace of subsequent dose increases should be even slower than usual. Because they produce prominent side effects and can be dangerous in overdose, TCAs are also now reserved for patients unresponsive to other treatments. Refer to Chapter 3 for a more extensive discussion of the TCAs. 

Despite its considerable efficacy, clomipramine has given way to the SSRls as a result of their more favorable side effect and safety profiles. Clomipramine, however, is often used as an augmenfafion sfrategy for OCD pafienfs who are partial responders to SSRl therapy. The effectiveness of this approach has not been verified in confrolled frials. Furthermore, coadministration of clomipramine with some of the SSRls can result in potentially dangerous drug interactions. 

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