SHIONOGI QUALICAPS

Hard gelatin capsules may be made hermetically sealed by the technique of banding wherein a film of gelatin, often distinctively colored, is laid down around the seam of the cap and body. Parke Davis KapsealR is a typical example. In the Quali-SealR process (Shionogi Qualicaps), two thin layers are applied, one on top of the... 

Gelatin capsules are also produced, which contain 5%i Polyethylene glycol (PEG) 4000 as an additional plasticizer. They have improved physical characteristics over standard gelatin capsules and can loose more moisture before they become brittle. They were first developed by Shionogi Qualicaps in Japan, where they are widely used for pharmaceutical products. 

From Capsugel Multistate File and Shionogi Qualicaps Capsules Technical Information Manual. 

Calculated from the size of non-deforming plug, which fits inside a capsule closed to length specification of Shionogi Qualicaps Inc. Based on hole dimensions of Bosch (H K) machine dosing disc. 

Research Laboratories, Shionogi Qualicaps Co., Ltd, 321-5, Ikezawa-cho, Yamato-Koriyama, Kara 639-1032, Japan... 

The development of HPMC capsules is achieved by three specialized companies. The first is Shin-Etsu Chemical Co., Ltd. which specialized in a field of polymer science. The second is Shionogi Co., Ltd., an innovative pharmaceutical company and the last is Shionogi Qualicaps Co., Ltd., ahard capsule manufacturer. In particular, I very much appreciate of Dr. N. Muranushi s (Shionogi Co., Ltd.) kindly supports. 

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