Shelf life, flowables

A Computer-Based Technique for the Evaluation of Sedimentation Rates/Shelf Life of Pesticide Flowables... 

The formation of non-redispersible sediment in a pesticide flowable formulation is often the primary cause of product failure during inventory/sheIf storage. In order to develop and maintain a quality pesticide flowable formulation, a formulator needs evaluation techniques which will enable him to quickly determine the relative stability performance of a sample in a non-subjective manner. Accurate sample characterization and early prediction of shelf life is also highly desirable. Many methods for flowable sample evaluation, such as sediment probing, are subjective and destructive to the integrity of the sample. Often, samples have to be aged at elevated temperatures to obtain measurable differences in stability performance within reasonable time constraints. The purpose of this paper is to describe equipment and methodology which can be utilized to measure the relative... 

Since the first commercial application to carbonless copy paper in the 1950s, microencapsulation with coacervation technology has been successfully applied to many other areas, such as food, pharmaceuticals, cosmetics, biotechnology, and agrochemicals. The capsules provide such functions as controlled release, taste masking, improved heat and oxidative stability, reduced volatility/ flammability/toxicity, separation of reactive incompatibles, improved shelf-life, conversion of liquids to solids, and improved flowability as well as material handling. Among various coacervation processes, complex coacervation is most prevalent. 

Tetracycline hydrochloride is in the Netherlands available in two qualities, microcrystalline and ponderosum ( heavy ). Tetracycline hydrochloride ponderosum consists of agglomerates of the microcrystalline substance and has a shelf life of 3 years, has a better flowability and is much less susceptible to degradation than the microcrystalline form. It is mainly used for capsule preparation. Because of the... 

Attempts to improve virus formulations have been primarily by the product registrant, especially private industry as this is where much of the formulation expertise exists. Commercial formulations have often been wettable powder, because the particulate nature of virus makes formulation of flowables difficult. Virus in dry formulations typically exhibits better shelf life than in liquid formulations (12). It must be noted, however, that not all dry formulations are stable, particularly those formulated as acetone precipitates. When formulated as an acetone extract, the early experimental formulations of Helicoverpa zea NPV, including Viron-H (International Minerals and Chemical Corp., Libertyville, IL) lost activity between shipment in the spring to the scientists... 

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