Sensor microarrays

One of the goals in sensor development is to generate multianalyte detection. OLED pixel arrays present an such sensors in a uniquely simple approach. Recently, been fabricated [45], which are promising for future arrays. Importantly, using combinatorial fabrication, ent colors can be fabricated next to each other. Such for PL-based sensors with analyte-sensitive markers wavelengths. 

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Ehrmann, S. Jungst, J. Goschnick, J. Automated cooking and frying control using a gas sensor microarray. Sensors and Actuators B 66 (2000) 43-45. 

Sysoev, V. V. Kiselev, I. Frietsch, M. Goschnick, J., Temperature gradient effect on gas discrimination power of a metal-oxide thin-film sensor microarray, Sensors 2004,... 

D. Walt, Optical sensor microarrays for explosives detection, in Electronic Noses and Sensors for the Detection of Explosives, (eds JW Gardner and J Yinon), NATO ASI Series, Kluwer Academic Pubhshers, Dordrecht, 2004. 

Musatov, V. Y., Sysoev, V. V., Sommer, M. and Kiselev, I. (2010) Assessment of Meat Freshness with Metal Oxide Sensor Microarray Electronic Nose A Practical Approach, Sens. Actual B, 144,99. 

The advances in hybrid nanotechnology involving nucleic acids are mostly linked with sequence-specific nucleic acid interactions. Ti02-oligonucleotide nanocomposites retain the intrinsic photocat-alytic capacity of Ti02 as well as the bioactivity of the oligonucleotide DNA therefore, the developments in this area have been oriented toward cellular imaging and protein or DNA sensor microarrays [38]. 

Ransley JHT, Watari M, Sukumaran D, McKendry RA, Seshia AA (2006) SU8 bio-chemical sensor microarrays. Microelectron Eng 83 1621-1625... 

FIGURE 6-20 Configuration of a penicillin sensor based on an microarray electrode coated with a pH-responsive polypyrrole. Vq = gate voltage VD = drain voltage ID = drain current PS = potentiostat CE and RE = counter and reference electrodes, respectively. (Reproduced with permission from reference 76.)... 

A poly(aniline boronic acid)-based conductimetric sensor for dopamine consisting of an interdigitated microarray electrode coated with poly(aniline boronic acid) has also been developed by the Fabre team. The sensor was found to show a reversible chemoresistive response to dopamine without interference by ascorbic acid from their mixtures.42... 

Fig. 3.27 KAMINA gas sensor chip with gradient microarray mounted in its housing.

Fig. 3.29 Resistances of the 38 sensor segments of a Sn02-microarray equipped with Si02-membrane during alternating exposure to carbon monoxide contaminated humid air and clean air with the same relative humidity...

However, in addition to its low production costs and excellent gas analytical features, the gradient microarray chip offers further advantages over the classical arrays consisting of separate gas sensors of different chemistry. Since all sensor ele-... 

Fig. 3.34 LDA of the microarray signal patterns obtained in practical KAMINA tests to detect gaseous precursors of smoldering fires through overheated cable insulation. Prior to the LDA the measured resistances of the sensor segments were normalized to the median of all sensor segments and the number of variables was reduced by a Principal Component Analysis (PCA) to cutback the noise. Clear distinction is achieved between clean air...

Fig. 3.36 LDA of the microarray signal patterns measured in a meeting room during night and day. The room temperature was about 22°C in all cases. Data were collected at two meetings a week apart and in the empty room with an isopropanol source at a distance of 0.8 m from KAMINA. The resistances of the sensor segments are normalized by reference and by median. Clearly the air of the empty room with closed and opened windows can be distinguished from the lower air...

The formulation of the ORMOSIL precursor is chosen in the light of screening experiments (Figure 6.13). For the recognition of ovalbumin, for example, the precursor is a 55 mol% TEOS, 2 mol% 3-aminopro-pyltriethoxysilane (APTES), 3 mol% n-octyItrimethoxysi 1 ane (C8-TMOS) and 40 mol% bis(2-hydroxyethyl)aminopropyltriethoxysilane (HAPTS) mixture. The resulting microarray sensor exhibits analytical... 

Bioresorbable polymers, 3 735-740 Bioselective adsorption, 6 387 Biosensors, 3 794-815 14 154 22 269 affinity DNA biosensors, 3 805-808 affinity immunosensors, 3 800-805 applications, 3 812-813 biomimetic sensors, 3 809-810 catalytic, 3 796-799 cellulose ester applications, 5 408 comparison with microarrays, J6 38It evolution of, 16 380-381 production by thick-film technology, 3 810-812... 

Immunoaffinity chromatography (IAC), 6 400—402 12 137, 145 Immunoanalyzers, automated, 14 150 Immunoassay(s), 14 135-159. See also Immunoassay- DNA probe hybrid assays Immunoassay methods Immuno(bio)sensors antibody-antigen reaction, 14 136-138 basic technology in, 14 138-140 chemiluminescent, 14 150-151 classification of, 14 140-153 design of, 14 139-140 enzyme, 14 143-148 fluorescence, 14 148-150 highly specific, 14 153 historical perspective on, 14 136 microarrays and, 14 156—157 microfluidics in, 26 968—969 monoclonal versus polyclonal antibodies in, 14 152-153... 

The organic conductor properties of tetrathiaflulvalenetetracyanoquino-dimethane (TTF-TCNQ) as a material for constructing electrodes, viz. its catalytic response and resistance to passivation, are of special interest for the determination of biological compounds, which usually have slow electrode kinetics and a low sensitivity, and tend to foul electrode surfaces. The response of a TTF-TCNQ microarray sensor inserted in a flow system for... 

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