Semliki Forest virus structure

The initial event in the entry of viruses into cells is the attachment of the virus to specific receptors on the cell membrane. The chemical structures of most receptors for animal viruses are poorly defined. Cell surface glycoprotein, glycolipids, and phospholipids have been implicated. Very recently Helenius et al. (29) could identify human HLA and murine H-2 histocompatibility antigens as receptors for Semliki Forest virus these antigens are well-defined membrane glycoproteins. 

Another general role of post-translational cleavage of polypeptide chains in viral systems is the specific processing of structural proteins leading to the assembly of the virus (44,45). In this respect, the semliki-Forest virus may be considered as an interesting model to find out how proteins which have different cellular locations reach their final sites within the cell. A single messenger RNA directs the synthesis of the viral capsid protein and of two membrane proteins. 

E. coli. See Escherichia coU El glycoprotein atomic structure, of Semliki Forest virus (SFV), 381... 

SEM methods. See Scanning electron microscopy (SEM) methods Semliki Forest virus (SFV), 61, 353-354 El Ca backbone, 382 El glycoprotein atomic structure of, 381 resolution reconstruction of, 62 Semliki Forest virus (SFV) /tick-bome... 

Bron RJ, Wahlberg M, Garoff H, Wilschut J. Membrane fusion of Semliki Forest virus in a model system Correlation between fusion kinetics and structural changes in the envelope glycoprotein. EMBO J. 1993 12 693-701. 

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