Seminal vesicles, growth

Stimulation of secretion in seminal vesicles Growth of dog prostate... 

Lawton and Whitsett (376), observed that application of urine from male deer mice Peromyscus maniculatus bardii, when applied to the nose of young males retarded seminal vesicle growth but removal of olfactory bulbs of males at 3 weeks of age blocked the inhibitory response. 

V. Hormonal Regulation of Adult Seminal Vesicle Growth and... 

Dyck, M.K., Gagne, D., Ouellet, M., Senechal, J.-F., Belanger, E., Lacroix, D., Sirard, M.-A., and Pothier, F. 1999. Seminal vesicle production and secretion of growth hormone into seminal fluid. Nature Biotechnology 17, 1087-1090. 

Exposing young male prairie deer mice, Peromyscus maniculatus, to soiled bedding from adult male conspecifics retards the growth of their testes and seminal vesicles. Male, but not female, urine applied to the nose has the same effect. Removal of the olfactory lobes at the age of 3 weeks blocks this effect (Lawton, 1979). The reproductive development of male California voles, M. californicus, is suppressed hy chemical cues from the mother (Rissman etah, 1984). 

These steroids control the development of male characteristics sperm production and growth of the sex organs (penis, testes), prostate, and seminal vesicles (their androgenic... 

The androgens stimulate the development of the male secondary structures, such as the penis, scrotum, seminal vesicles, prostate gland, vas deferens and epididymis. The deepening of the voice, the growth of pubic, axillary, body, and facial hair, as well as the development of the characteristic musculature of the human male, are also under the influence of testosterone. If the testes fail to develop or are removed prior to puberty, these changes do not occur. Thus, testosterone is essential for reproductive function of the male. 

Growth, age at balano-preputial separation, serum T4 and TSH, weight of seminal vesicles, levator ani/ bulbocavernosus muscle, and ventral prostate... 

Fujii and Villee (124) reported that RNA, isolated by cold phenol extraction from the vesicular glands of adult rats or immature testosterone-treated animals and then treated with DNase and pro-nase, can stimulate growth and incorporation of labeled leucine into protein when the RNA is instilled into the central lumen of the seminal vesicles of immature or postpubertal rats. Treatment of the RNA preparations with RNase abolished these effects. RNA from seminal vesicle of an untreated immature or orchiectomized adult rat was ineffective. In more recent experiments from the same laboratory (125), the vesicular gland RNA from sexually mature rats was extracted with cold phenol, treated with DNase and ethanol and ether, and then separated into poly(A) RNA and poly(A) RNA fractions by chromatography on Sepharose 4B-inidylic acid. When the desalted RNA fractions were instilled into seminal vesicles of castrated rats, only the poly(A) RNA... 

Testosterone 17p-hydroxy-androst-4-en-3-one, an important androgen synthesized in the interstitial cells of the testicle. It stimulates growth of the prostate and seminal vesicles, and promotes sperm maturation and development of male secondary sexual characteristics. Apart from mammalian testes, T. also occurs in blood and urine. It was first isolated in 1935 from bovine testes. Esters of X, e.g. T. propionate, are used in the treatment of male sex hormone deficiency, endocrine disorders in gynecology and in geriatrics. For structure and biosynthesis, see Androgens. 

In the male, the penis is enlarged and may reach adult sizes at a very early age. The scrotum, the prostate, and the seminal vesicles develop precociously. The hair of the beard, the axillary regions, and the pubis grows in infancy. The general body growth of the child is accelerated, yet the adult male pseudohermaphrodite is usually shorter than normal because the epiphysis closes prematurely in patients with excess androgens. 17-Ketosteroid secretion in the urine is markedly elevated, but it can be normalized rapidly by the administration of small doses of cortisone. 

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