Poisoning selenium

Selenium deficiency is not as well documented as selenium poisoning, but may be equally significant. 

In livestock, there are three basic types of selenium poisoning ... 

Palmer IS, Olson OE. 1979. Partitial prevention by cyanide of selenium poisoning in rats. Biochem Biophys Res Comm 90 1379-1386. 

Lee T, Tera F (1986) The meteoritic chromium isotopic composition and limits for radioactive Mn in the early solar system. Geochim Cosmochim Acta 50(2) 199-206 Lemly AD (1985) Toxicology of selenium in a freshwater reservoir Implications for environmental hazard evaluation and safety. Ecotoxicol Environ Saf 10 314-338 Lemly AD (1998) Pathology of Selenium Poisoning in Fish. In Environmental Chemistry of Selenium. 

Skorupa JP (1998) Selenium poisoning of fish and wildlife in nature Lessons from twelve real-world-examples. In Environmental Chemistry of Selenium. Frankenberger Jr. WT, Engberg RA (eds), Marcel Dekker, New York, p 315-354... 

The most well-documented case of selenium poisoning in the environment is that of the Kesterson... 

An endemic disease in China, characterized by loss of hair and nails, skin lesions, and abnormalities of the nervous system, including some paralysis and hemiplegia, was attributed to chronic selenium poisoning. The daily intake for six affected individuals averaged 5.0mg versus 0.1 mg for people from an unaffected area. Changing the diet led to... 

Unlabeled Uses Antimony poisoning, bismuth poisoning, selenium poisoning, silver poisoning, vanadium poisoning... 

Contraindications Acute renal impairment, organic (short-chain alkyl) mercury poisoning, G6PD deficiency (unless a life-threatening situation exists), hepatic insufficiency (unless due to arsenic poisoning), use of iron, cadmium or selenium poisoning, hypersensitivity to dimercaprol or any component of the formulations... 

Some plants classified as mineral accumulators become toxic because of the inorganic materials that they absorb from soil and water and retain in the plant biomass. An important example of such a plant is Astragalus, sometimes called locoweed. This plant causes serious problems in some western U.S. grazing areas because it accumulates selenium. Animals that eat too much of it get selenium poisoning, characterized by anemia and a condition known descriptively as blind staggers. ... 

Human selenosis has been reported from the Enshi district, Hubei Province, China. Between 1923 and 1988,477 cases of human selenosis were reported, 338 resulting in hair and nail loss and disorders of the nervous system. In one small village, the population was evacuated after 19 of 23 people suffered nail and hair loss, and all the livestock had died from selenium poisoning. Cases of selenosis in pigs reached a peak between 1979 and 1987, when 280 out of 2,238 pigs were affected in one village. 

Moxon A. L. (1937) Alkali disease or selenium poisoning. In South Dakota State College Bulletin, vol. 311, 99p. 

---