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Selectively Bred Rat Lines

One recent selectively bred rat fine is the rat model of high and low anxiety-related behavior, developed by Landgraf and colleagues (Liebsch et al. 1998). Wistar rats displaying either extremely high (HAB) or low (LAB) anxiety-related behavior on the elevated plus maze (see Sect. 2.2.2) were selected and bred over a decade (Liebsch et al. 1998). The resulting two rat fines distinctly [Pg.51]

Carr LG, Foroud T, Bice P et al. Mapping of a quantitative locus for alcohol consumption in selectively bred rat lines. Alcohol Clin Exp Res 1998 22 884-887. Bice P, Foroud T, Bo R et al. Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines. Mamm Genome 1998 9 949-955. [Pg.439]

Henniger MSH, Ohl F, HOlter SM, Weifienbacher P, Toschi N, Lorscher P, Wigger A, Spanagel R, Landgraf R (2000) Unconditioned anxiety and social behaviour in two rat lines selectively bred for high and low anxiety-related behaviour. Behav Brain Res 111 153-163... [Pg.64]

Liebsch G, Linthorst ACE, Neumann ID, Reul JMHM, Holsboer F, Landgraf R (1998) Behavioral, physiological, and neuroendocrine stress responses and differential sensitivity to diazepam in two Wistar rat lines selectively bred for high and low anxiety-related behavior. Neuropsychopharmacology 19 381-396 Lister RG (1990) Ethologically based animal models of anxiety disorders. Pharmacol Ther 46 321-340... [Pg.66]

Overstreet DH, Friedman E, Matlie AA, Yadid G (2005) Tlie Flinders Sensitive Line rat A selectively bred putative animal model of depression. Neurosci Biobehav Rev 29 739—759. [Pg.510]

See other pages where Selectively Bred Rat Lines is mentioned: [Pg.49]    [Pg.50]    [Pg.52]    [Pg.59]    [Pg.49]    [Pg.50]    [Pg.52]    [Pg.59]    [Pg.430]    [Pg.431]    [Pg.138]   


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Line Selection

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