Seed extract

Contraction in the number of EPA-allowed biocides has heightened efforts to develop naturally derived preservatives and microorganisms capable of countering microbial degradation. Neem oil A. dirachta indica seed extract) has been featured as an exceptional natural candidate for the preservation of cosmetic products. Naturally derived chemicals with antimicrobial properties have been used since antiquity as preservatives. However, displacement of successhil synthetic products by natural products in preservatives of any category remains to be witnessed. 

Pyrazol-1 -ylalanine, an isomer of histidine, was isolated from Citrullus vulgaris (watermelon) seed and its structure was confirmed by comparison with synthetic material 107). It was the major free amino acid in the dormant dry seed but was present in only trace amounts in vegetative tissue. While present in seed extracts of other members of the Cucurbitaceae, it has not been identified as occurring in members of other plant families. 

Nakamura, Y., Tsuji, S., and Tonogai, Y, Analysis of proanthocyanidins in grape seed extracts, health foods and grape seed oils, J. Health Set, 49, 45, 2003. 

Tetrahydroxyflavone Luteolin Seed extract Medicago saliva S. meliloli... 

Preservatives which are based on natural ingredients or nature identical are small in numbers and these are gaining the attention of marketers. The ones I am aware of are - Grapefruit Seed extracts and Usnic Acid distributed by Paroxite, Neem seed oil... 

Seed extracts Guar gum Locust bean gum Psyllium seed Quince seed... 

Bocco A, Guvelier ME, Richard H and Berset C. 1998. Antioxidant activity and phenolic composition of citrus peel and seed extracts. J Agric Food Chem 46 2123-2129. 

For chromatographic purification of ergot alkaloids from seed extracts see Phytochem. 11,1479(1972). 

Fig. 2.61. Separation of grape seed extract (a) and grape seed extract spiked with mixture of eight compounds (b) using optimized conditions. Chromatographic conditions are discussed in the text. Peak identification 1 = 2-phenylethanol 2 = vanillin 3 = ferulic acid 4 = protocatechoic acid 5 = caffeic acid 6 = gallic acid 7 = catechin 8 = epicatechin. Reprinted with permission from A. Kamangerpour et al. [167].

A. Kamangerpour, M. Ashraf-Khorassani, L.T. Taylor, H.M. McNair and L. Charida, Supercritical fluid chromatography (SFC) of polyphenolic compounds in grape seed extract. Chromatographia 55 (2002) 417 -21. 

Dietary intervention with crude MegaNatural-AZ grape seed extract significantly reduced (by 30-50%) Alzheimer s disease-type cognitive deterioration in mice by prevention of amyloid formation in the brain [8]. However, it is essential to determine which components of the extract exhibited bioactivity in the transgenic... 

Kohler N, Wray V, Winterhalter P (2008) Preparative isolation of procyanidins from grape seed extracts by high-speed counter-current chromatography. J Chromatogr A 1177 114-125... 

Antifungal activity of tea seed cake and tea seed extract. Chulalongkorn Med J 1981 24(4) 953-959. 

DC059 Majumder, P. K., and M. Gupta. Effect of the seed extract of carrot Daucus carota Linn.) on the growth of Ehrlich ascites tumor in mice. Phytoter Res 1998 12(8) 584-585. 

DC164 Kaliwal, B. B., and M. A. Rao. Inhibition of implantation by carrot seed extract and its rectification by progest- DC 176 erone in albino rats. J Kamatak Univ... 

Kawagishi, S., T. Oosawa, and H. SI089 Katsuzaki. Pinoresinol glycoside, sesame seed extract containing the glycoside, and its use for preventing oxidation of lipids. Patent-Japan Kokai SI090 Tokkyo Koho-06,116,282 1994 5 pp. 

Krueger, C.G. et al. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of polygalloyl polyflavan-3-ols in grape seed extract, J. Agric. Food Chem., 48, 1663, 2000. 

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