Sedimentation field-flow fractionation polydisperse particle

FIG. 2.1 Sedimentation field flow fractionation (SdFFF) (a) an illustration of the concentration profile and elutant velocity profile in an FFF chamber and (b) a schematic representation of an SdFFF apparatus and of the separation of particles in the flow channel. A typical fractionation obtained through SdFFF using a polydispersed suspension of polystyrene latex spheres is also shown. (Adapted from Giddings 1991.)... 

This paper outlines the basic principles and theory of sedimentation field-flow fractionation (FFF) and shows how the method is used for various particle size measurements. For context, we compare sedimentation FFF with other fractionation methods using four criteria to judge effective particle characterization. The application of sedimentation FFF to monodisperse particle samples is then described, followed by a discussion of polydisperse populations and techniques for obtaining particle size distribution curves and particle densities. We then report on preliminary work with complex colloids which have particles of different chemical composition and density. It is shown, with the help of an example, that sedimentation FFF is sufficiently versatile to unscramble complex colloids, which should eventually provide not only particle size distributions, but simultaneous particle density distributions. 

Sedimentation field-flow fractionation was used also for the kinetic study of HAP particles aggregation in the presence of various electrolytes to determine the rate constants for the bimolecular process of aggregation and to investigate the possible aggregation mechanisms describing the experimental data. The HAP sample contained polydisperse, irregular colloidal particles with number-average diameter = 0.262 0.046 p-m. 

Koliadima, A. Karaiskakis, G. Sedimentation field-flow fractionation A new methodology for the concentration and particle size analysis of dilute polydisperse colloidal samples. J. Liq. Chromatogr. 1988,11, 2863. 

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