Scopolia japonica

Scopolia japonica. Leaves, 0-18 hyoscyamine and norhyoscj mine. ... 

Hyoscine (Scopolamine, Atroscine), Ci,H2i04N. The name hyoscine was first used by Hohn and Reichardt for the basie hydrolytic product of hyoscyamine, now known as tropine. It was subsequently used by Ladenburg for a supposed isomeridc of atropine, Cj HjgOjN, isolated from the mother liquors of hyoscyamine. This was found by Schmidt, Hesse and others to be identical with scopolamine, Ci,H2i04N, obtained by Schmidt from Scopolia japonica. The name hyoscine has priority and is in use, but scopolamine is also employed, especially in Germany. 

Although there are some differences in the degree of enhancement of extractability, among the modifiers employed in this study, 10% methanol basified with diethylamine was found to be optimal for the extraction of hyoscyamine (1) and scopolamine (2) from both the roots and aerial parts of Scopolia japonica. While the recoveries from the roots and aerial parts of S. 

Scopolia japonica 427, 428 Senecio 419 S. cordatus 419 S. inaequidens 419 Spiraea 2... 

Calystegine Aj Physalis alkekengi vat.francheti (Solanaceae) Scopolia japonica (Solanaceae) roots Hyoscyamus niger (Solanaceae) leaves/roots Lycium chinense (Solanaceae) roots ... 

Naturally occurring hyoscine is a combination of laevo-tropic acid with inactive hyoscine. It is found, mostly in conjunction with hyoscyamine, in many species of Datura. In D. arborea, D. fastuosa, and D. metel, the alkaloid consists chiefly of hyoscine whilst D. stramonium contains principally hyoscyamine, with some hyoscine. It is present also in Scopolia and Hyoscyamus species, for instance in Scopolia japonica and Hyoscyamus niger. 

Scopolia japonica Maxim. Solanaceae Chi, Jap stem leaves sedative for convulsions used with other ingredients 35... 

Atropine, scopolamine Scopolia japonica Hairy roots 1.3% DW 347... 

Romeike 382) reported that several cultures of Datura species grown on 2,4-D were unable to esterify tropine with tropic acid. Only a D. innoxia culture grown on NAA was capable of this bioconversion. Scopolia lurida, Hyoscyamus niger, and Atropa belladonna were incapable of any esterification of tropine. Hiraoka et al. 383) could not confirm these results with their Datura cell lines, but they found that D. innoxia is capable of acetylation of other compounds, such as pseudotropine, scopine, and scopoline, as well. A series of other plants tested, for example, Atropa belladonna and Scopolia japonica, were unable to carry out such an... 

Mano Y, Nabeshima S, Matsui C, Ohkawa H (1986) Production of tropane alkaloids by hairy root cultures of Scopolia japonica. Agric Biol Chem 50 2715-2722 Mano Y, Ohkawa H, Yamada Y (1989) Production of tropane alkaloids by hairy root cultures of Duboisia leichhardtii transformed by Agrobacterium rhizogenes. Plant Sci 59 191-201... 

Scopolia japonica grows wild in Japan, and this plant contains (—)-hyoscyamine and (—)-scopolamine. The rhizomes and roots of S. japonica are known as Roto root, and the extract of this material is used as an analgesic, for spasmolysis, and as a digestive juice secretion suppressor. Originally, Roto was prepared from the rhizome and root of Hyoscyamus niger var. chinensis, which grows wild in China. 

Asano N, Kate A, Kizu H, Matsui K, Watson AA, Nash RJ (1996) Calystegine B4, a novel inhibitor from Scopolia japonica. Carbohydrate Res 293 195-204... 

Isol. from Scopolia japonica, Hedera helix and others. Mp 217-219°. 

The a-L-fucosidase activity of culture filtrates of Scopolia japonica calluses have been investigated by isoelectric focusing. ... 

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