Scale-Up of PTC Systems

Phase transfer catalysis has been widely employed in commercial synthetic applications, primarily because of its ability to replace organic amine and alkoxides bases with low cost metal hydroxides. An example of this from PTC Organics 

Phase transfer catalysis exemplifies how a laboratory curiosity can successfully make the transition to becoming a routine process, and PTC is now commonly featured in many general chemistry texts. It has been applied to numerous processes, both large and small scale [18]. 

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