Salmonella aeruginosa

Specific bacteriostatic activity against Escherichia coli (681, 896, 899), Staphylococcus aureus (681, 896), Cocci (900), Shigella dysenteriae (681), Salmonella ryphi (681), Proteus vulgaris (681), Pseudomonas aeruginosa (681), Streptococcus (889, 901, 902) and Pneumococcus (901-904). 

Whereas these preparations do not possess the high bacteriostatic activity of quaternary ammonium germicides, they have the alternate advantage of being rapidly functional in acid solution. In comparative experiments of several different disinfectants, the acid—anionic killed bacteria at lower concentration than five other disinfectants. Only sodium hypochlorite and an iodine product were effective at higher dilution than the acid—anionic. By the AO AC use dilution test, the acid—anionic killed Pseudomonas aeruginosa at 225 ppm. Salmonella choleraesuis at 175 ppm, and Staphylococcus aureus at 325 ppm (172). 

The types of microorganisms found in various products are Pseudomonas species, including Pseudomonas aeruginosa, Salmonella, species, Staphylococcus aureus, and Escherichia coli. The USP and other pharmacopoeias recommend certain classes of products to be tested for specified microbial contaminants, e.g., natural plant, animal, and some mineral products for the absence of Salmonella species, suspensions for the absence of E. coli, and topically administered products for the absence of P. aeruginosa and S. aureus. Emulsions are especially susceptible to contamination by fungi and yeasts. Consumer use may also result in the introduction of microorganisms. For aqueous-based products, it is therefore mandatory to include a preservative in the formulation in order to provide further assurance that the product retains its pharmaceutically acceptable characteristics until it is used by the patient. 

Following the identification of KDO in Escherichia coli,29,31 Pseudomonas aeruginosa,9 and Salmonella typhimurium33 several studies were made in order to determine the possible presence of KDO in... 

In P. aeruginosa PAO, the degree of hydroxylation, that is, lipid A heterogeneity with respect to hydroxylated [12 0(2-OH)] and nonhydroxylated (12 0) fatty acids, was found to be mainly influenced by the growth temperature. With increasing temperature, the proportion of the nonhydroxylated fatty acids (12 0 and 16 0) was decreased at the expense of such hydroxylated ones as 12 0(2-OH)(144). Asimilar finding was made with Salmonella species (142). 

PHARMACOLOGICAL ACTIVITIES AND CLINICAL TRIALS Antibacterial activity. Alcohol extract of black tea, assayed on Salmonella typhi and Salmonella paratyphi A, was active on all strains of Salmonella paratyphi A, and only 42.19% of Salmonella typhi strains were inhibited hy the extract ". Ffot water extract of the dried entire plant and the tannin fraction, on agar plate, were active on Escherichia coli. Pseudomonas aeruginosa, and Staphylococcus aureus. ... 

Antibacterial activity. Decoction of the dried fruit, on agar plate, was inactive on Pseudomonas aeruginosa ° Ethanol (95%) and water extracts of the dried fruit, on agar plate at a concentration of 50 p,L/plate, were inactive on Staphylococcus aureus ° Water extract of the dried fruit, on agar plate, at a concentration of 1 mg/mL, was inactive on Salmonella typ/ii ". Hot water extract of the dried fruit, on agar plate at a concentration of 62.5 mg/mL, was inactive on Escheri chia coli and Staphylococcus aureus ° . 

Other infections caused by E. coli, K. pneumoniae, Enterobacter, Salmonella typhi, N. gonorrhoeae, N. meningitidis, H. influenzae, H. ducreyi, Shilgella, Vibrio cholerae. Pseudomonas aeruginosa. Staph, aureus etc. 

Citrobacter freundii Enterobacter cloacae Escherichia coli Klebsiella pneumoniae Proteus vulgaris Pseudomonas aeruginosa Salmonella typhimurium Serratia marcescens Shigella spp. Staphylococcus spp. Streptococcus spp. Candida albicans Saccharomyces cerevisiae Acanthamoeba castellani Paramecium caudatum Tetrahymena pyrifomds... 

Absence of Specified Organisms (S. aureus, P. aeruginosa, E. coli and Salmonella spp.)... 

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