Rifampicin tablets

Ranitidine Tablet Cores (150 mg) Ranitidine Tablet Cores (300 mg) Riboflavin see Vitamin B2 Rifampicin Tablets (450 mg)... 

Tablet-associated esophagitis has been reported in a 70-year-old white man on the fourth day of antibiotic therapy with vancomycin, gentamicin, and oral rifampicin for Staphylococcus epidermidis prosthetic valve endocarditis (50). 

The authors noted that age, bedridden state, gastroesophageal reflux disease, simultaneous administration of several medications, and nasopharyngeal obstruction may have increased the risk of esophagitis. They found a second case of tablet-associated esophagitis caused by rifampicin in their review of the published literature. 

There have been no reports on the risk of Pneumocystis jiroveci pneumonia in patients taking rifampicin plus co-trimoxazole prophylaxis. Until such time as more data are available, it is prudent to use double-strength co-trimoxazole tablets twice daily for prophylaxis of toxoplasmosis and P. jiroveci pneumonia in patients taking concomitant rifampicin. 

In 10 HIV-positive patients who had been taking one double-strength tablet of co-trimoxazole daily for more than 1 month, the concentrations of trimethoprim and sulfamethoxazole in serum were significantly reduced after the administration of rifampicin (199). 

Figure 10.17 Plasma concenirations of rifampicin (RMP) after oral administration in solution (10 mg kg ) given alone (A), with p

A study in 6 healthy subjects found that after taking rifampicin 450 mg daily for 6 days, the maximum serum level of diclofenac, measured 8 hours after a single 100-mg dose of an enteric-coated tablet, was reduced by 43% and the AUC was reduced by 67% ... 

WHO. International pharmacopoeia monograph on rifampicin, isoniazid, pyrazinamide and ethambutol hydrochloride tablets. Working document QAS/04.097 rev Oct 05. Quality Assurance Safety Medicines (QSM), Department of Essential Drugs and Medicines Policy (EDM). WHO Geneva, October, 2005. 

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