Tricarbonyl rhenium

Despite a common perception that organometallic chemistry essentially belongs in the province of catalysis rather than in vivo applications because of high reactivity of metal carbon bonds, certain organometallic species have very high kinetic stability. Indeed, this point is highlighted by the present wide application of the isonitrile complex Tc(ses-tamibi), [Tc(2-methoxyisobutylisonitrile)6]+, in myocardial imaging. Rhenium tricarbonyl and cyclopentadienyl complexes offer further ex-... 

Scheme 28. Manganese and rhenium tricarbonyl complexes with sohd phase linkers (68).

Stable rhenium tricarbonyls bonded to the surface of MgO have been prepared and characterized by EXAFS. Heating under He, O2 or vacuum of a sample obtained by impregnation of Re2(CO)io produced the oxidative fragmentation of the initial surface organometallic species [39-41]. These types of supported well-characterized species can be used as models in the study of reaction mechanisms [42]. 

Preparation of a polylactide containing a 2-bis( picolylamine) rhenium tricarbonyl terminus... 

Table 1 Rhenium tricarbonyl complexes with multidentate ligands...

Rhenium tricarbonyl complexes containing substituted cyclopentadi-enyl and bis diphenylphosphine ligands also were investigated as anticancer agents. The antiproliferative effects on breast cancer of complex A shown in Fig. 23 were examined relative to the known active metabolite, 4-hydroxy tamoxifen, and found to have a similar effect [107]. The cytotoxicity of five rhenium tricarbonyl bis-diphenylphosphine complexes B shown in Fig. 23 was examined for 18 different human cancer cell lines. The tests showed that all the complexes were active against specific tumor cell lines, especially a line of breast and uterine cancer [108]. 

Summary of Structural Assignments and IR Spectra of Rhenium Tricarbonyls on MgO (Papile and Gates, 1992)... 

Top S, Vessieres A, Pigeon P, Rager MN, Huche M, Salomon E, Cabestaing C, Vaissermann J, Jaouen G (2004) Selective estrogen receptor modulators (SERMs) in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and Biological behaviour. Chem-biochem 5 1104—1113... 

Understandably, there is an enormous richness in the photophysical and photochemical behavior of the excited states present in diimine rhenium tricarbonyl complexes. Indeed, this plethora of molecular photophysical characteristics has led to a wide range of interesting and important applications, including their use as catalysts [21-25], sensors [26-33], probes for photo-polymerization [10, 34, 35], optical switches [36 15], light-emitting materials [46-52], nonlinear optical materials [53-56], binding or photocleavage of DNA [57-61], and radiopharmaceuticals [62-66], Under the purview of this article our focus will be to cover photophysical and photochemical properties and hence other aspects, such as synthetic, catalytic, pharmaceutical, etc., will not be discussed. 

Metal-Directed Macrocyclic Complexes Incorporating Diimine Rhenium Tricarbonyl Moieties... 

Benzenechromium tricarbonyl (Fluorobenzene)chromium tricarbonyl Cyclopentadienyl)rhenium tricarbonyl (1,3-Cyclohexadiene)iron tricarbonyl (1,3-Cyclohexadienyl)manganese tricarbonyl (T rimethylenemethane)iron tricarbonyl (Cyclopentadienyl)manganese tricarbonyl (1,3-Butadiene)iron tricarbonyl... 

One drawback of rhenium tricarbonyl complexes, /bc-[Re(bpy) (COlaL]", is that their absorption of visible light is weak (see... 

Rhenium Tricarbonyl-( 5-trimethyl-silyl-cyclopentadienyl)- E18, 137 [Dien + Re(CO)]... 

Mixed-ligand rhenium tricarbonyl complexes anchored on a (k2-H, S) trihydro(mercaptoimidazolyl)borate A missing binding motif for soft scorpionates Mo 1 V/ /Re oc / 84... 

The number of technetium and rhenium tricarbonyl compounds in preclinical evaluation is remarkable. These efforts comprise small molecules as well as macromolecules useful in diagnostic and/or therapeutic nuclear medicine. There are also clinical data available with tumor affine peptides such as neurotensin receptor- and somatostatin receptor-targeting peptides radiolabeled with the Tc(CO)3 core. 

ReN202PC34Hj2, Rhenium, (V-cyclopenta-dienyl) ( 1 -(1-naphthal-enyl)ethyl] amino]caibonyl] nitrosyl(tri-phenylphosphine)-, (+)-(SR)-, 29 217 ReOjCjHs, Rhenium, tricarbonyl(Ti -cyclo-pentadienyl)-, 29 211... 

Development of technetium and rhenium-tricarbonyl labeled radiopharmaceuticals 13MOL3206. 

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