Retinoic acid receptor-related orphan

Retinoic acid receptor-related orphan receptor a (RORct) has been recently deorphanized, cholesterol been identified as its ligand. RORct is expressed in many tissues and is therefore a regulator of multiple biological processes. A beneficial modulatory role of RORct is proposed in the pathogenesis of dyslipidemia, inflammation and atherosclerosis. ... [Pg.103]

Jakel, H., Fruchart-Najib, J., Fruchart, J. C. Retinoic acid receptor-related orphan receptor alpha as a therapeutic target in the treatment of dyslipidemia and atherosclerosis. Drug News Perspect. 2006, 19, 91-97. [Pg.105]

F 1 retinoic acid receptor-related orphan RORa 0 2... [Pg.472]

ER Estrogen Receptor, AR Androgen Receptor, GR Glucocorticoid Receptor, TR Thyroid Receptor, RAR Retinoic Acid Receptor, RXR Retinoie X Receptor, PR Progesterone Receptor, VDR Vitamin D Receptor, PPAR Peroxisome Proliferator-Activated Receptor, PXR Pregnane X Receptor, ROR Retinoic Acid-Related Orphan Receptor, NHF-4 Hepatocyte Nuclear Eactor 4, ERR Estrogen-Related Receptor... [Pg.2]

Abbreviations IR inverted repeat DR direct repeat ER everted repeat NR no repeat . Numbers of the HREs give the number of pairs separating the half-sites. R purine, Y pyrimidine. NGFI Nerve growth factor induced receptor COLfP-TF Chicken ovalbumin upstream promoter transcription factor ROR Retinoic acid related orphan receptor, a, P und y are receptor subtypes coded by distinct genes. After Mangelsdorf et al., 1995. [Pg.150]

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