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Retinoic acid chromatography

Baillet, A., Corbeau, L., Rafidson, R, and Ferrier, D., Separation of isomeric compounds by reversed-phase high-performance liquid chromatography using Ag+ complexation. Application to cis-trans fatty acid methyl esters and retinoic acid photoisomers, /. Chromatogr., 634, 251, 1993. [Pg.51]

Retention time, in chromatography, 6 374-375, 409-410 ( )-Reticuline, 2 90 Retina, 7 307-308 Retinal, 25 787. See also Vitamin A carotenes and, 25 790 Retinitis pigmentosa, 17 659 Retinoic acid, 25 787-789, 790. See also Vitamin A... [Pg.803]

H. M. M. Arafa, F. M. A. Hamada, M. M. A. Elzamar and H. Nau, Fully automated determination of selective retinoic acid receptor ligands in mouse plasma and tissue by reversed-phase liquid chromatography coupled on-line with solid-phase extraction , J. Chromatogr. A 729 125-136(1996). [Pg.295]

Quantification of Endogenous Retinoic Acid in Human Plasma by Liquid Chromatography/Mass Spectrometry... [Pg.166]

Bempong, D.K., Honigberg, I.L., and Meltzer, N.M. (1993) Separation of 13-cw and all trans retinoic acid and their photodegradation products using capillary zone electrophoresis and micellar electronic chromatography (MEC), J. Pharm. Biomed. Anal., 11, 829-833. [Pg.405]

Lehman, P.A. Franz, T.J. A sensitive high-pressure liquid chromatography/particle beam/mass spectrometry assay for the determination of all-trans-retinoic acid and 13-cis-retinoic acid in human plasma. J.Pharm.Sci., 1996, 85, 287-290... [Pg.1223]

Barua, A.B. Kostic, D. Barua, M. Olson, J.A. Determination of retinol and retinoic acid in capillary blood by high-performance liquid chromatography. J.Liq.Chromatogr., 1995, 18, 1459-1471... [Pg.1224]

Lefebvre, P. Agadir, A. Comic, C. Gourmel, B. Hue, B. Dreux, C. Degos, L. Chomienne, C. Simultaneous determination of all-frans and 13-cis retinoic acids and their 4-oxo metabolites by adsorption liquid chromatography after solid-phase extraction. J.Chromatogr.B, 1995, 666, 55-61... [Pg.1225]

Takeda, N. Yamamoto, A, Simultaneous determination of 13-cis- and all-trans-retinoic acids and retinol in human serum by high-performance liquid chromatography. J.Chromatogr.B, 1994, 667, 53—59... [Pg.1226]

Sundquist, A.R. Stahl, W. Steigel, A. Sies, H. Separation of retinoic acid all-trans, mono-cis and poly-cis isomers by reversed-phase high-performance liquid chromatography. J.Chromatogr, 1993, 637, 201-205... [Pg.1231]

Guiso, G. Rambaldi, A. Dimitrova, B. Biondi, A. Caccia, S. Determination of orally administered all-trans-retinoic acid in human plasma by high-performemce liquid chromatography. J.Chromatogr.B, 1994, 656, 239—244 [all-trans-retinyl acetate (IS) extracted metabolites, isotretinoin, tretinoin LOD 10 ng/mL pharmacokinetics non-interfering allopurinol, amikacin, aracytin, ceftazidime, ciprofloxacin, doxorubicin, fluconazole, prednisone]... [Pg.1232]

Sass, J.O. Nau, H. Single-run analysis of isomers of retinoyl- J-D-glucuronide and retinoic acid by re-versed-pheise high-performance liquid chromatography. J.Chromatogr.A, 1994, 685, 182-188 [LOD... [Pg.1233]

Ranalder, U.B. Lausecker, B.B. Huselton, C. Micro liquid chromatography-mass spectrometry with direct Uquid introduction used for separation and quantitation of all-(rans- and 13-cis-retinoic acids and their 4-oxo metabolites in human plasma. J.Chromatogr., 1993, 617, 129-135 [LC-MS LOQ 0.3 ng/mL extracted metabolites, isotretinoin, tretinoin]... [Pg.1233]

Vane, F.M. Stoltenborg, J.K. Bugge, C.J. Determination of 13-cis-retinoic add and its major metabolite, 4-oxo-13-cis-retinoic acid, in human blood by reversed-phase high-performance liquid chromatography. J.Chromatogr, 1982, 227, 471-484 [gradient whole blood extracted metabolites, isotretinoin, tretinoin, vitamin A LOQ 10 ng/mL pharmacokinetics]... [Pg.1233]

Source From Determination of aR-trans- and 13-cis-retinoic acids by two-phase, two-dimensional thin layer chromatography in creams and by high-performance thin-layer chromatography in gel formulations, in J. Chromatogr. ... [Pg.1390]

Besler et al. [671] studied retinal and retinol isomer retention on a silica column (A = 325nm or 371 nm) with hexane/MlBE (97/3 and 93/7), hexane/dioxane (93/7 and 94/6), and heptane/MrBE (94/6 and 93/7) mobile phases. The purpose of this work was to find an accq)table replacement for dioxane, namely, MrBE. The best overall chromatography resulted when 94/6 hexane/dioxane resolved 11,13-di-cis-, 13-CIS-, 9,11-13-tri-cis-, 9,13-di-cis-, 11-cis-, 7,1 l-di-c , 9-cis-, 7,9-di-cis, and all-tra s retinol in 15 min. Broader peaks but better resolution were obtained for the same solute set when 93/7 hexane/MtBE was used (elution was complete in 21 min), MlBE in hexane also gave excellent resolution of 13-c/s-retinoic acid and z -trans retinoic acid methyl esters on a silica column (A = 340 nm) in <5 min, whereas dichloromethane/hexane (35/65) required 17 min and toluene/hexane (45/55) required 10 min. It was found that for the toluene/hexane mobile phase, very small changes in the water content of the system dramatically and adversely affected the chromatography. The MrBE/hexane mobile phase provided more overall stability with respect to these changes. [Pg.301]

Paust, 1977). Irradiation of retinoic acid (3) in heptane, in the presence of iodine, with a fluorescent lamp gave the two isomeric 4-keto acids (188) and (193), which can be separated by chromatography (McKenzie et aL, 1978b),... [Pg.73]

Retinol-11,12- H2 of low specific activity has been prepared (Isler et al., 1960) based on the work of Isler et al. (1947) on the synthesis of retinyl acetate. The same sequence of reactions as shown in Fig. 8, with several improvements in technique because of the small scale, was applied by Perry et al. (1982) to the preparation of retinoic acid tritiated at very high specific activity. Pure, recrystallized diol (XXVI) was partially hydrogenated with tritium over Lindlar catalyst in the presence of quinoline and the dihydro compound (XXVII), acety-lated in such a way as to afford mainly the monoacetate (XXVIII). Exposure of the acetate at low temperature for a very short time to very dilute hydrogen bromide in methylene chloride gave, after chromatography, pure retinyl-11,12- H2 acetate (XXIXa). Simultaneous hydrolysis and oxidation of the retinyl acetate by silver oxide in aqueous methanolic sodium hydroxide then yielded all-fran -reti-noic-11,12- H2 acid (Vllh). The specific activities obtained ranged from 25 to 40 Ci/mmol. [Pg.158]

See other pages where Retinoic acid chromatography is mentioned: [Pg.574]    [Pg.45]    [Pg.18]    [Pg.519]    [Pg.519]    [Pg.574]    [Pg.1041]    [Pg.704]    [Pg.201]    [Pg.1233]    [Pg.1233]    [Pg.328]    [Pg.903]    [Pg.903]    [Pg.1232]    [Pg.1233]    [Pg.1390]    [Pg.1581]    [Pg.969]    [Pg.5]    [Pg.117]   
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