Resorcinal

Alkali Fusion of /u-Benzenedisulfonic Acid. Even though this process like the previous one is a very ancient one, it is still the main route for the synthesis of resorcinol. It has been described in detail previously and does not seem to have drastically evolved since 1980. It involves the reaction of benzene with sulfuric acid to form y -benzenedisulfonic acid which is then converted to its disulfonate sodium salt by treatment with sodium sulfite. In a second step, this salt is heated to 350°C in the presence of sodium hydroxide yielding the sodium resorcinate and sodium sulfite. 

Resorcine Brown R [5850-16-8] (27) (Cl Acid Brown 14, Cl 20195) is a symmetrical primary disazo dye with bihmctional coupling component (resorcinol). 

The measurment in twophase systems is discussed by the example of dithizonate of zinc, in pseudomonophase systems - by the example of zinc and cadmium complexes with l-(2-pyridylazo)-2-naphthol, lanthanoid ion complexes with l-(2-pyridylazo)-resorcin. 

Covalent and noncovalent combination of porphyrins as well as calix[4]arenes, resorcin[4]arenes including macroheterocyclic fragments, and cyclodextrins by construction of supramolecular artificial receptors 98EJ02689. 

Cineol forms a number of crystalline derivatives, amongst which may be mentioned the hydrobromide, CjgHjgO. HBr, melting at 56°, and the compound with iodol, CjdHjgO. C I NH, which forms yellowish-green crystals, melting at 112°. It also forms a crystalline compound with resorcinol, which has been used as a basis for its quantitative determination. This compound consists of 2 molecules of cineol with 1 of resorcin, and forms needle-shaped crystals, melting at 80°. 

Schimmel Co. recommend the absorption of the cineol by a 40 to 50 per cent, solution of resorcin in water, and reading the unabsorbed portion in the neck of a Hirschsohn flask. 

Messrs. Schimmel Co. have since modified the method by recommending the oil to be first fractionated and the portion boiling between 170° to 190° C. to be treated with the resorcin solution. In some cases this gives results fairly concordant with the phosphoric acid method usually adopted, as the following results will show —... 

Cineol by Direct Absorption with Resorcin Solution. Cineol by Absorption with Resorcin after Fractionation. Cineol by Phosphoric Acid Process. 

In other cases, however, the results obtained are obviously too high. An oil which yielded 95 per cent, distilling between 170° to 190° C., all of which was absorbed by resorcin solution, had the following characters —... 

The detection of phthalic acid by fusion with resorcin has been found to be unreliable as a fluorescein reaction is frequently obtained with pure oils. 

Resorbierung, /. resorption, reabsorption. Resorcin, n. resorcinol, resorcin, -blau, n, resorcin blue, -gelb, n. resorcin yellow. Resorzin, n. resorcinol, resorcin, reap., abbrev. of respektive. respektive, adv. respectively, or rather, or. Respirationsnahrungsnuttel, n. respiratory food. 

Pb mononitro resorcinate, and NC priming material are followed by a chlorate, charcoal, lacquer mixt for flame and fire transfer, and protective coatings of clear lacquer form a bulb resembling a book-match tip. Ignition is achieved by a current of 500mA for a minimum of 50msec. This is one example of a series of electric matches which are manufd to various current input requirements with different chemical compos... 

Letessier S (1989) Chemical peel with resorcin. In Roenigk RK, Roenigk HH (eds) Dermatologic surgery principles and practice. Marcel Dekker, New York,p1017... 

Trichloroacetic acid 25-50% lotion Trichloroacetic acid 25-30% gel Unna paste (resorcin 40%)... 

After identification of A9-THC as the major active compound in Cannabis and its structural elucidation by Mechoulam and Gaoni in 1964 [66], a lot of work was invested in chemical synthesis of this substance. Analogous to the biosynthesis of cannabinoids, the central step in most of the A9-THC syntheses routes is the reaction of a terpene with a resorcin derivate (e.g., olivetol). Many different compounds were employed as terpenoid compounds, for example citral [67], verbenol [68], or chrysanthenol [69]. The employment of optically pure precursors is inevitable to get the desired (-)-trans-A9-THC. 

Van De Water, R. W. Ph.D. Thesis, Alkylation and dearomatization of resorcinal derivatives A synthetic route towards scyphostatin. University of California, Santa Barbara, 2003. 

Capsules are instantly formed by simple addition of two equivalents of Pd(dppp)(OTf)2 (dppp = l,3-bis(diphenylphosphino)propane) to acetone, CH2C12 or CHC13 solutions of resorcin [4]arene derivatives having four pyridine units as pendent groups, see Figure 64.637... 

Electron-rich aromatic systems can act efficiently as Michael donors, as shown recently by Krohn s group (Scheme 2.46) [111]. For example, reaction of the enone 2-193 with the resorcine derivative 2-194 in a domino Michael/acetalization process led to various naturally occurring xyloketals of type 2-196 in excellent yield. 

The placement of four pyridyl groups on the upper rim of the resorcin[4]arene cavitands was followed by the addition of Pd(II) ions to generate a monomeric molecular receptor with hydrophobic binding sites <00TL3113>. The treatment of 2,4,6-rm[(4-pydrinyl)methyl-sulfanyl]-l,3,5-triazene (tpst) with silver to form a single-stranded one-dimensional coordination polymer, [Ag7(tpst)(C104)2(N03)5(dmf)2] , which contains nanotubes... 

LI. Lacap re, J., Badin, J., Renier, J. C., Weissbach, R., and Basset, G., Vitesse de sedimentation des hematics, reaction de Vemes k la resorcine, indice dliapto-globine au cours des rhumatismes. Rev. rhumat. 24, 690 (1957). 

Chupakhin et al. investigated the reactivity of some [l,2,4]triazolo[l,5- ]pyrimidines with resorcine (Scheme 17) <1999IZV1573>. These authors found that 147 reacts with resorcine to give at first the addition product 148 which undergoes an intramolecular cyclization to produce the bridged skeleton 149. 

Silylated 1,4-cyclohexadienes, such as 58, are accessible by the Birch reduction of resorcin dimethyl ether and subsequent one-pot silylation-methylation. The reduction of bromo adamantane with 58, occurs readily in the presence of the radical initiator AIBN, with the driving force being the aromatization leading to 59 (Scheme 14). 

P.R.90 is derived from the fluorescein structure (147). Fluorescein is a yellow dye with intensely green fluorescence which was discovered by A.v.Bayer in 1871. It is prepared by heating resorcin and phthalic anhydride with zinc chloride or concentrated sulfuric acid ... 

Fig. 9.2 (a) X-ray crystal structure of 1 and (b) the snub cube, one of the 13 Archimedean solids. The square faces of the snub cube correspond to the resorcin[4]arenes the eight shaded triangles that adjoin three squares correspond to the water molecules of 1. 

The discovery that members of the resorcin[4]arene family self-assemble to form 1, owing to its classification as an Archimedean solid, prompted us to examine the topologies of related spherical hosts with a view to understanding their structures on the basis of symmetry. In addition to providing grounds for classification, we anticipated that such an approach would allow us to identify similarities at the structural level, which, at the chemical level, may not seem obvious and may be used to design large, spherical host assemblies similar to 1. 

We have recently demonstrated the ability of six resorcin[4]arenes and eight water molecules to assemble in apolar media to form a spherical molecular assembly which conforms to a snub cube (Fig. 9.3). [10] The shell consists of 24 asymmetric units - each resorcin[4]arene lies on a four-fold rotation axis and each H2O molecule on a three-fold axis - in which the vertices of the square faces of the polyhedron correspond to the corners of the resorcin[4]arenes and the centroids of the eight triangles that adjoin three squares correspond to the water molecules. The assembly, which exhibits an external diameter of 2.4 nm, possesses an internal volume of about 1.4 A3 and is held together by 60 O-H O hydrogen bonds. 

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