Release of genetically altered

Back in 1983, for example, the Subcommittee on Investigations and Oversight concluded that one of the major risks associated with the release of genetically altered organisms was not necessarily the releases themselves, but our inability and failure to make risk assessments. Four years later, we still haven t developed adequate standards for risk assessment... 

The EPA approved the release of the first genetically engineered crop, gene-altered tobacco plants. 

Activation of epithelial cells release of reactive oxygen/ nitrogen species causing DNA damages/genetic alteration... 

Autoimmunity. Autoimmune diseases are disorders of immune regulation in which several different factors (e.g. viral, genetic, hormonal, environmental) may each play a role. Autoimmune diseases may belong to any of the four Coombs and Cell classifications of hypersensitivity and include the production of autoantibodies, destructive inflammatory cell infiltrates in various organs, and deposition of immune complexes in vascular beds. Chemically induced autoimmunity may result from any of several possible mechanisms. These include the alteration or release of autoantigens, or the cross-reaction of the chemical with autoantigens, or alternatively a direct effect on the immune system via lymphocytes or macrophages (60). 

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