Regulation of glycosylation

Involvement of Nucleotide Sugar Transporters in the Regulation of Glycosylation... [Pg.1152]

M. Demetriou, M. Granovsky, S. Quaggin, and J. W. Dennis, Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation, Nature, 409 (2001) 733-739. [Pg.160]

CMP, CDP, CTP, and synthetic derivatives of these nueleotides have been found to inhibit sialyltransferase activity.301" 02 Interest in such inhibitors is increasing, as they may be expected to serve as anticancer agents.269 901,303 Therefore, regulation of Golgi sialyltransferase activity appears possible by nucleotides as products of sialyl- and other glycosyl-transferase activities.1" 2 Interestingly, Epstein-Barr virus infection of human B, lymphoblastoid cell-lines leads to a diminution of sialyltransferase activity.304... [Pg.194]

Anti-glycosyl antibodies isolated from the sera of some animals immunized with bacterial carbohydrate antigens are of a restricted heterogeneity, that is, they occur in relatively few, multimolecular forms.145 146 Such antibodies have been used in studies on the structure of antibodies,147 and on the genetic regulation of synthesis of anti-... [Pg.440]

Stable Analogs of Glycosyl Phosphates, the Main Glycosylating Agents and Metabolic Regulators... [Pg.59]

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