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Regulation kappa-opioid receptors

Bohn LM, Belcheva MM, Coscia CJ (2000) p-opioid agonist inhibition of kappa-opioid receptor-stimulated extracellular signal-regulated kinase phosphorylation is dynamin-dependent in C6 glioma cells. J Neurochem 74 574-581... [Pg.367]

Spangler R., Bo A., Zhou Y., Maggos C., Yuferov V., Kreek M. Regulation of kappa opioid receptor mRNA in the rat brain by binge pattern cocaine administration and correlation with preprodynorphin mRNA. Mol. Brain Res. 38 71, 1996. [Pg.103]

Chu P, Murray S, Lissin D, von Zas-trow M. Delta and kappa opioid receptors are differentially regulated by dyna-min-dependent endocytosis when activated by the same alkaloid agonist. J Biol Chem 1997 272 27124-27130. [Pg.487]

Liu-Chen LY. Agonist-induced regulation and trafficking of kappa opioid receptors. Life Sci. 2004 75 511-536. [Pg.51]

Agonist occupancy of GPCRs, such as the delta opioid receptor, leads to physiological effects through interactions with heterotrimeric G proteins. Such G proteins consist of a Ga subunit and its Gpy dimeric partner. There are four major families of Ga proteins with different profiles of effector interaction 1) Gas, which activate adenylyl cyclase 2) Gai/o, so-called inhibitory G proteins named for their ability to inhibit adenylyl cyclase, but interact with many effectors 3) Gaq/11, which activate phospholipase C- 3 (PLC- 3) and 4) Gal2/13, which may regulate small GTP-binding proteins. Delta opioid receptors, like mu and kappa opioid receptors, couple to mem-... [Pg.89]

Manzanares J, Lookingland KJ, Moore KE (1990b) Kappa-opioid-receptor-mediated regulation of a-melanocyte-stimulating hormone secretion and tuberohypophysial dopaminergic neuronal activity. Neuroendocrinology 52 200-205. [Pg.512]

Manzanares J, Wagner EJ, LaVigne SD, Lookingland KJ, Moore KE (1992b) Sexual differences in kappa opioid receptor-mediated regulation of tuberoinfundibular dopaminergic neurons. Neuroendocrinology 55 301-307. [Pg.512]

Suzuki S, Chuang LE, Doi RH, Bidlack JM, Chuang RY (2001) Kappa-opioid receptors on lymphocytes of a human lymphocytic cell line morphine-induced up-regulation as evidenced by competitive RT-PCR and indirect immunofluorescence. Int Immuno-pharmacol 1 1733-1742. [Pg.564]

Tallent M, Dichter M. Reisine T. Coupling of the cloned kappa and mu opioid receptors to cellular effector systems is differentially regulated. Neuroscience 1998 85 873-885. [Pg.484]

Table 8.1 shows a selective timeline of the evaluation, abuse, and regulation of butorphanol, an opioid with mixed activity at mu and kappa receptors. The most salient aspects of the drug s recent history can be summed up in terms of two questions ... [Pg.153]

Tu B, Timofeeva O, Jiao Y et al (2005) Spontaneous release of neuropeptide Y tonically inhibits recurrent mossy fiber synaptic transmission in epileptic brain. J Neurosci 25 1718-29 Ueda H, Fukushima N, Ge M et al (1987) Presynaptic opioid kappa-receptor and regulation of the release of Met-enkephalin in the rat brainstem. Neurosci Lett 81 309-13 van den Pol AN, Gao XB, Obrietan K et al (1998) Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin. J Neurosci 18 7962-71... [Pg.434]

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See also in sourсe #XX -- [ Pg.91 ]



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