Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Hypocretin/Orexin

Zeitzer JM, Nishino S, Mignot E (2006) The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. Trends Pharmacol Sci 27 368-74... [Pg.913]

Siegel JM (2004) Hypocretin (orexin) role in normal behavior and neuropathology. Annu Rev Psychol 55 125-148... [Pg.913]

Nishino S, Ripley B, Overeem S, et al. Hypocretin (orexin) deficiency in human narcolepsy. Lancet 2000 355 39-40. [Pg.632]

Figure 1.6 (A) Changes in c-Fos IR in hypocretin/orexin(HCRT+)- containing neurons in response to BIC treatment as a function of distance from the microdialysis probe. The percentage of double-labeled cells was greatest closer to the probe (grids 1 and 2, compared with 3 and 4) and was greater with higher concentrations or exposure times. Contralateral cells were not affected. (B) Much lower percentages of melanin-concentrating hormone (MCH+) exhibited c-Fos IR activation in response to BIC. From Alam et al. (2005). Figure 1.6 (A) Changes in c-Fos IR in hypocretin/orexin(HCRT+)- containing neurons in response to BIC treatment as a function of distance from the microdialysis probe. The percentage of double-labeled cells was greatest closer to the probe (grids 1 and 2, compared with 3 and 4) and was greater with higher concentrations or exposure times. Contralateral cells were not affected. (B) Much lower percentages of melanin-concentrating hormone (MCH+) exhibited c-Fos IR activation in response to BIC. From Alam et al. (2005).
Figure 1.8 Effects of local POA warming on a PLH wake-active, REM-off, putative hypocretin/orexin-containing neuron. POA warming suppressed the waking-related discharge of PLH neurons, in the absence of any state change. The PLH receives strong projections from all subregions of the POA, including GABAergic projections. From Methippara et al. (2003). Figure 1.8 Effects of local POA warming on a PLH wake-active, REM-off, putative hypocretin/orexin-containing neuron. POA warming suppressed the waking-related discharge of PLH neurons, in the absence of any state change. The PLH receives strong projections from all subregions of the POA, including GABAergic projections. From Methippara et al. (2003).
Brown, R. E. (2003). Involvement of hypocretins/orexins in sleep disorders and narcolepsy. Drug News Perspect. 16, 75-9. [Pg.48]

Horvath, T. L., Peyron, C., Diano, S. et at (1999). Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. J. Comp. Neurol 415, 145-59. [Pg.102]

Mileykovskiy, B. Y., Kiyashchenko, L. I. Siegel, J. M. (2005). Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron 46, 787-98. [Pg.105]

Bernard, R., Lydic, R. Baghdoyan, H. A. (2006). Hypocretin (orexin) receptor subtypes differentially enhance acetylcholine release and activate G protein subtypes in rat pontine reticular formation./. Pharmacol. Exp. Ther. 317, 163-71. [Pg.135]

Mignot, E. (2004). Sleep, sleep disorders and hypocretin (orexin). Sleep Med. 5 (suppl. 1), S2-8. [Pg.171]

Li, Y Gao, X. B., Sakurai, T. van den Pol, A. N. (2002). Hypocretin/orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system. Neuron 36, 1169-81. [Pg.242]

Espana, R. A., Baldo, B. A., Kelley, A. E. Berridge, C. W. (2001). Wake-promoting and sleep-suppressing actions of hypocretin (orexin) basal forebrain sites of action. Neuroscience 106, 699-715. [Pg.398]

Grivel, J., Cvetkovic, V., Bayer, L. el al. (2005). The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation. J. Neurosci 25, 4127-30. [Pg.399]

Hungs, M. Mignot, E. (2001). Hypocretin/orexin, sleep and narcolepsy. Bioessays 23, 397-408. [Pg.399]

Baumann, C. R. Bassetti, C. L. (2005). Hypocretins (orexins) and sleep-wake disorders. Lancet Neurol. 4, 673-82. [Pg.427]

Bayer, L., Serafin, M., Eggermann, E. et al. (2004). Exclusive postsynaptic action of hypocretin-orexin on sublayer 6b cortical neurons. J. Neurosci. 24, 6760-4. [Pg.427]

Kohlmeier, K A., Inoue, T. Leonard, C. S. (2004). Hypocretin/orexin peptide... [Pg.429]

See other pages where Hypocretin/Orexin is mentioned: [Pg.8]    [Pg.10]    [Pg.17]    [Pg.18]    [Pg.48]    [Pg.51]    [Pg.52]    [Pg.54]    [Pg.56]    [Pg.57]    [Pg.68]    [Pg.77]    [Pg.95]    [Pg.104]    [Pg.104]    [Pg.105]    [Pg.107]    [Pg.171]    [Pg.173]    [Pg.215]    [Pg.240]    [Pg.298]    [Pg.388]    [Pg.400]    [Pg.428]    [Pg.428]    [Pg.429]    [Pg.429]    [Pg.430]   
See also in sourсe #XX -- [ Pg.33 , Pg.34 , Pg.35 ]



SEARCH



Hypocretins

Orexins

Role of orexins hypocretins

© 2024 chempedia.info