Reactions with Ammonia and Amines

Reaction with ammonia and amines (Sec tion 20 14) Acyl chlorides react with am monia and amines to form amides A base such as sodium hydroxide is normally added to react with the hydrogen chio ride produced... 

Reaction with ammonia and amines (Section 20 14) Acid an hydrides react with ammonia and amines to form amides Two molar equivalents of amine are required In the example shown only one acyl group of acetic anhydride becomes incor porated into the amide the other becomes the acyl group of the amine salt of acetic acid... 

Reactions with Ammonia and Amines. Acetaldehyde readily adds ammonia to form acetaldehyde—ammonia. Diethyl amine [109-87-7] is obtained when acetaldehyde is added to a saturated aqueous or alcohoHc solution of ammonia and the mixture is heated to 50—75°C in the presence of a nickel catalyst and hydrogen at 1.2 MPa (12 atm). Pyridine [110-86-1] and pyridine derivatives are made from paraldehyde and aqueous ammonia in the presence of a catalyst at elevated temperatures (62) acetaldehyde may also be used but the yields of pyridine are generally lower than when paraldehyde is the starting material. The vapor-phase reaction of formaldehyde, acetaldehyde, and ammonia at 360°C over oxide catalyst was studied a 49% yield of pyridine and picolines was obtained using an activated siHca—alumina catalyst (63). Brown polymers result when acetaldehyde reacts with ammonia or amines at a pH of 6—7 and temperature of 3—25°C (64). Primary amines and acetaldehyde condense to give Schiff bases CH2CH=NR. The Schiff base reverts to the starting materials in the presence of acids. 

Reaction with ammonia and amines (Section 20.14) Acid anhydrides react with ammonia and amines to form amides. 

D. M. Roundhill, Chem. Rev. 92, 1-27 (1992) . .Transition Metal and Enzyme Catalyzed Reactions involving Reactions with Ammonia and Amines". 

The siloxy derivative is more reactive than the methoxy analog in substitution reactions with ammonia and amines (114). 

Steinbach, J., Herrmann, E.. and Riesel, L., Reaction of the two-component system trialkyl phos-phite/carbon tetrachloride with nucleophiles containing hydrogen. Part 2. Reaction with ammonia and amines, Z. Anorg. Allg. Chem., 523, 180, 1985. 

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