Radio novel developments

Reliable criteria to identify the (individual) patients suitable for high-LET radiation therapy need to be developed. At present, the available criteria are derived (mainly) from the clinical fast neutron experience. It can be expected that novel approaches based on modern techniques involving molecular biology or gene identification may provide appropriate and still missing information. They may also provide information on the susceptibility or risk for secondary radio-induced cancer. 

A homogeneous and sensitive HTRF binding assay was developed to allow prosecution of an HTS campaign for novel small molecule Hsp90 inhibitors. The HTRF assay was based on a non-radio-active resonance energy transfer between a donor label (europium chelate) and an acceptor label (allophycocyanin [APC]) brought into close proximity by a specific binding interaction. 

Langmuir s discoveries helped shape the establishment of modern radio and television broadcasting, safeguarded the lives of soldiers in war, and provided the framework that allowed his research team to develop a key to possibly control the weather. Bernard Vonnegut s brother, the writer Kurt Vonnegut, made Langmuir a character, Dr. Felix Hoenikker, in his novel Cat s Cradle. Vonnegut claims that the absentminded scientist really did leave a tip for his wife after breakfast one time and abandoned his car in the middle of a traffic jam. 

A novel modular probe base was designed. A universally applicable probe base to be used in radio frequency applications such as NMR imaging and spectroscopy was developed. The concept is to support several arbitrarily combinable rf channels as well as additional devices, for example, a climate... 

In addition to the development of these novel materials the number of possible applications for more standard plastic/polymeric materials will continue to grow and the future for plastics in electronics is certainly an exciting one. With doped polymeric materials actually forming the active components of many semiconductor devices, it may not be too long before polymer-based semiconductors, solar cells and batteries are in routine production and the all-plastic transistor radio becomes a reality. 

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