Pycnogenol pine bark

Pycnogenol (= Pine bark Pinus maritima (Pinaceae) [bark] proanthocyanidins)... 

Moini, H., Guo, Q., and Packer, L., Enzyme inhibition and protein-binding action of the procya-nidin-rich french maritime pine bark extract, pycnogenol effect on xanthine oxidase, J. Agric. 

In addition, 125 mg of the herbal alternative to aspirin, namely pine bark extracts4 containing bio-pycnogenol, have the same effect as 500 mg aspirin as an anti-blood clotting agent. It is an alternative for people who have stomach ulcers. 

Pycnogenols are a heterogeneous group of flavonoids from French maritime pine bark. The name pycnogenols is a term which was given for the designation of flavan-3-ol derivatives by Masquelier et al. [70]... 

Thanks to the experience of one of my readers, I know that generic pine bark extract may not produce the blood pressurelowering effects of Pycnogenol. That particular reader, by the way, is an M.D. involved in research at a major pharmaceutical company. He s been following my cholesterol program for many years, and started on the blood pressure program after reading about it in my publication. The Diet-Heart Newsletter. 

Pycnogenol, a particular formulation of French Maritime pine bark extract, which also has been proven in human clinical studies to effectively lower blood pressure. Only the French Maritime formulation has been tested, so other products containing pine bark extract may not work. The recommended dosage is 200 mg daily. To locate a number of Internet distributors of Pycnogenol, go to www.pycnogenol. com or call 877-369-9934. 

Liu, X. Wei, J. Tan, F. Zhou, S. Wurthein, G. Rohdewald, P. Pycnogenol, french maritime pine bark extract, improves endothelial function of hypertensive patients. Life Sci. 2004, 74 (7), 855-862. 

Rohdewald, P. A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacology. Int. J. Clin. Pharmacol. Ther. 2002, 40 (4), 158-168. 

The use of pine bark extracts has its roots in ancient traditional medicine in different countries of the world. In general, the utilization of Pycnogenol in the past was considered suitable for many of those conditions where vitamin C deficiency is now known to be involved, such as scurvy, skin disorders, and wound heating. Ttiis utilization anticipated the understanding of the complex nature of the interaction between different antioxidants and the important role that polyphenols may play in the recycling and interplay with other antioxidants and, finally, in human health and disease. 

Drehsen, G., From ancient pine bark uses to Pycnogenol, in Antioxidant Food Supplements in Human Health, Hiramatzu, M., Packer, L., and Yoshikawa, T., Eds., Academic Press, San Diego, 1998. 

Bito, T., Roy, S., Sen, C.K., and Packer, L., Pine bark extract pycnogenol downregulates IFN-gammainduced adhesion of T cells to human keratinocytes by inhibiting inducible ICAM-1 expression. Free Radical Biol. Med., 28, 219-227, 2000. 

Packer, L., Rimbach, G., and Virgili, F. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus martima) bark, pycnogenol, Free Radic. Biol. Med., 27, 704—724, 1999. 

Going back to Pycnogenol and how it helped Cartier s men fight scurvy, it took centuries to learn that the pine needles provided a small amount of vitamin C and the bark yielded vitamin C-supercharging bioflavonoids, members of the polyphenol family of plant-derived substances. In fact, it was only in 1984 that... 

The standardized extract from the bark of the French maritime pine is one of the most utilized heibal-sourced food supplements in the world. It is patented under the brand name of Pycnogenol ,... 

---