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PXR Regulation of Cholesterol Metabolism

Tzameli, I., Pissios, P., Schuetz, E. G., and Moore, D. D. (2000) The xenobiotic compound l,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Mol. Cell Biol. 20, 2951-2958. [Pg.177]

Bledsoe, R. K., Consler, T. G., Stimmel, J. B., Goodwin, B., Liddle, C., Blanchard, S. G., Willson, T. M., et al. (2000) Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J. Biol. Chem. 275, 15122-15127. [Pg.177]

Tzameli, I., Chua, S. S., Cheskis, B., and Moore, D. D. (2003) Complex effects of rexinoids on ligand dependent activation or inhibition of the xenobiotic receptor, CAR. Nucl. Recept. 1, 2. [Pg.177]

Yamada, H., Yamaguchi, T., and Oguri, K. (2000) Suppression of the expression of the CYP2B1/2 gene by retinoic acids. Biochem. Biophys. Res. Commun. 277, 66-71. [Pg.177]

Kakizaki, S., Karami, S., and Negishi, M. (2002) Retinoic acids repress constitutive active receptor-mediated induction by l,4-bis[2-(3,5-dichloropyridyloxy)]benzene of the CYP2B10 gene in mouse primary hepatocytes. Drug Metab. Dispos. 30, 208-211. [Pg.177]


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