Purge panel

Ignition controls shall include upstream (in flare header prior to knockout drum) dual flow sensing equipment which shall start the automatic flare purge, pilot ignition and the flare ignition cycle. N P Refinery will be responsible for the wiring between the flow sensors and the ignition control panel. 

Ensure that hazard warning panels/compartment labels are removed/covered when any/all of the substances have been unloaded and the tank/compartment has been cleaned or purged - such that the dangerous substance remaining is insufficient to create a risk. 

Arindam Bose (Pfizer Central Research) further discussed the ICH documents and presented a rationale for the recommended combination of test procedures and process clearance validations required to demonstrate that marketed biopharmaceuticals are free of adventitious agents. He showed that testing of Pre-Seed Stock (PSS), the Master Cell Bank (MCB), and the Working Cell Bank (WCB) is required to demonstrate that they are free from contamination by mycoplasma, bacteria, molds, and yeasts. In addition, viral clearance validation studies must be performed on scaled down versions of each chromatographic step and the viral inactivation/removal step employed in the product purification scheme. Finally, clearance studies must be conducted with a panel of relevant and model viruses (typically three to four) to establish that the purification scheme will indeed purge any viruses that may be inadvertently introduced during processing. 

Panel Vibration Isolators/Strip Heaters/Purge/Other panels Required Local/Lube 011/Other. 

Figure 11 shows the result of the instantaneous normalization for a solution of Alexa-532 fluorophore dye complex (http //www.ingenta.com) at a concentration of 367 pg mL The top panel shows the counts corresponding to the excitation band and the middle panel is the fluorescent emission data. The lower panel is the normalized data. The figures show ten cycles of stop-and-flow measurement, between each cycle the fluid was purged from the capillary. 

Common maintenance tasks that can be easily performed by the user are the replacement of solvent filters (sinkers), in-line filters, check valves, and piston seals. Most modern HPLC pumps are designed for easy maintenance, with front panel access to many internal components. Figure 10.1 is a diagram of a slide-out pump unit showing the two pump heads with check valves, the purge valve, the in-line filter, and other components. Procedures for replacing some consumable items are summarized below ... 

The various Reactor Control panels allow the operator to review much more detailed information on the operation of an individual microreactor channel. It also allows the operator to make changes to the process set points. Figure 12.15 shows the Reactor Control panel for channel A of the microreactor on Reactor Board 1. Here, the operator can choose the gas stream flowing to the microreactor (either feed gas or purge gas), specify the gas flow rate, and define the set points for the microreactor heaters. The Temperature Reading indicators at the top of the channel block in the middle of the panel show the measured temperatures of the first six microreactor heaters in the channel using the microreactor RTDs (as... 

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