Pulmonary pathology

In early pulmonary disease, a patient may be hyperventilating while breathing room air so that the Paco2 is decreased, yet the Pa<>2 be relatively normal with such pulmonary pathology the P(A-a) 2 be increased. With frank pulmonary... 

Shen HH, Ochkur SI, McGarry MP, Crosby JR, et al. 2003. A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse. J Immunol. 

Wells CL. Pulmonary pathology. In DeTurk WE, Cahalin LP, eds. Cardiovascular and Pulmonary Physical Therapy. New York McGraw-Hill 2004. 

Tomashefski, J. F. (1990) Pulmonary pathology of the adult respiratory distress syndrome. Clin. Chest Med. 11, 593-619. 

Smith JS, Tian J, Lozier JN, Byrnes AP. Severe pulmonary pathology after intravenous administration of vectors in cirrhotic rats. Mol Ther 2004 6 932-41. 

Fleischman RW, Baker JR, Rosenkrantz H. Pulmonary pathologic changes in rats exposed to marihuana smoke for 1 year. Toxicol Appl Pharmacol 30. 1979 47(3) 557-66. 

Dutta, K.K., Gupta, G.S.D., Mishra, A., Joshi, A., Tandon, G.S., Ray, P.K. (1988). Inhalation toxicity studies of methyl isocyanate (MIC) in rats. Part I Pulmonary pathology and geno-toxicity evaluation. Indian J. Exp. Biol. 26 177-82. 

Roy PE, Magnan-Lapointe F, Huy ND, Boutet M. Chronic inhalation of marijuana and tobacco in dogs pulmonary pathology. Res Commun Chem Pathol Pharmacol 1976 14(2) 305-17. 

Another example of problems in interpreting results in knockout mice is demonstrated by the following An important role of colony-stimulating factor (CSF) in hemopoiesis of myeloid lineage cells has been demonstrated. G-CSF was knocked out, animals were neutropenic and had decreased hemopoietic progenitors in bone marrow and spleen [24]. In contrast, mice with a null mutation in GM-CSF, which acts upstream to G-CSF in myeloid differentiation, demonstrated no impairment of hemopoiesis, but develop a characteristic pulmonary pathology [25]. Therefore, we have to interpret the results of our experiments with knockout mice with caution. 

Prince GA, Jenson AB, Hemming VG, Murphy BR, Walsh EE, Horswood RL, Chanock R. Enhancement of respiratory syncytial virus pulmonary pathology in cotton rats by prior intramuscular inoculation of formalin inactivated virus. / Virol. f986 57(3) 72i-728. 

Hammar SP. Common neoplasms. In Dail DH, Hammar SP, eds. Pulmonary Pathology. 2nd ed. New York Springer-Verlag 1994 1487-1579. 

Death. There is no reliable information regarding doses of Stoddard solvent that could cause death in humans. It is possible that exposure to very high concentrations of this petroleum distillate could pose a serious health hazard and possibly even cause death from central nervous system depression. However, death is unlikely unless there is an extremely high exposure, since Stoddard solvent contains very little of the smaller carbon chains (Cs and below) which are known to be highly volatile and highly toxic (Andrews and Snyder 1986). There is also a remote risk of death due to pulmonary pathology from aspiration (Ellenhorn and Barceloux 1988). Levels that may pose a mortality risk to humans are not known and cannot be determined from animal studies. Concentrations of 10,000 mg/m Stoddard solvent were lethal to cats (Carpenter et al. 1975a,... 

Nold JB, Petrali JP, Wall HG, Moore DH. Progressive pulmonary pathology of two organofluorine compounds in rats. Inhalation Toxicol. 1991 3 123-137. 

Diagnostic Pulmonary Pathology, edited by P. T. Cagle Particle-Lung Interactions, edited by P. GehrandJ. Heyder Tuberculosis A Comprehensive International Approach, Second Edition, Revised and Expanded, edited by L. B. Reichman and E. S. 

Other applications of HA are as follows wound healing by extracellular regeneration, epithelial regeneration, topical treatment of dry eye syndrome and Sjogren s syndrome. It is also used as a viscosity agent in pulmonary pathology for achieving alveolar patency and as a filler for wrinkles and cutaneous lines. 

Yousem SA. The pulmonary pathologic manifestations of the CREST syndrome. Hum Pathol 1990 21 467-474. 

Reyes CN, Wenzel FJ, Lawton BR, et al. The pulmonary pathology of farmer s lung disease. Chest 1982 81(2) 142-146. 

Freiman DG, Hardy HL. Beryllium disease the relation of pulmonary pathology to clinical course and prognosis based on a study of 130 cases from the U.S. Beryllium Case Registry. Hum Pathol 1970 1 25-44. 

Stanley E, Lieschke GJ, Grail D, et al. Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc Natl Acad Sci U S A 1994 91(12) 5592-5596. 

Cooke KR, Nishinakamura R, Martin TR, et al. Persistence of pulmonary pathology and ahnormal lung function in IL-3/GM-CSF/IL-5 heta c receptor-deficient mice despite correction of alveolar proteinosis after BMT. Bone Marrow Transplant 1997 20(8) 657%62. 

---