Pulmonary oxygenation

Pulmonary Oxygen Toxicity Radiation Pneumonitis "Shock Lung"... 

R. V. Padmanabhan, R. Gudapaty, I. E. Liener, B. A. Schwartz, and J. R. Hoidal, Protection against pulmonary oxygen toxicity in rats by the intratracheal administration of liposome-encapsulated superoxide dismutase or catalase, Am. Rev. Respir. Dis. 732 164 (1985). 

T., Kato, A., Chida, K. Possible therapeutic effect of direct haemoperfusion with a polymyxin B immobilized fibre column (PMX-DHP) on pulmonary oxygenation in acute exacerbations of interstitial pneumonia. Respirology 13 (2008) 452-460. 

Kushi, H., Miki, T., Okamaoto, K., Nakahara, J., Saito, T., Tanjoh, K. Early hemoperfusion with an immobilized polymyxin B fiber column eliminates humoral mediators and improves pulmonary oxygenation. Crit Care 9 (2005) R653-R661. 

Mitaka, C., Tsuchida, N., Kawada, K., Nakajima, Y., Imai, T., Sasaki, S. A longer duration of polymyxin B-immobilizcd fiber column hemoperfusion improves pulmonary oxygenation in patients with septic shock. Shock 32 (2009) 478-483. 

Of the hematological changes very occasionally noted, polycythemia appears to be secondary to reduced pulmonary oxygen exchange (see the Respiratory section in this monograph). 

NorAway WH, Petriceks R, Canty E, Bensch KG. Maturation as a factor in pulmonary oxygen toxicity a preliminary report. J Pediatr 85 (1979) 859-864. 

Wagner PD. Mathieu-Costello O et al. Protection against pulmonary oxygen toxicity by N-... 

Clark JM, Lambertsen CJ. Pulmonary oxygen toxicity a review. Pharmacol Rev 1971 23(2) 37-133. 

Wright WB. Use of the University of Pennsylvania Institute for Environmental Medicine procedure for calculation of pulmonary oxygen toxicity. US Navy Exp Diving Unit Rep 1972 2 72. 

Wagner, C.D., Wolyniec, W.W., LePlante, A.M., Marschman, K., Lubbe, K., Haynes, N., Rothlein, K and Letts, L.G. (1992). Intercellular adhesion molecule-1 contributes to pulmonary oxygen toxicity in mice. Lung 170, 267-279. 

The half-life of COHb is 4 h at rest at room air. It is shortened to 60 to 90 min if 100% oxygen is given using a face mask. Since more than 2 h at 100% oxygen can cause pulmonary oxygen toxicity, the oxygen concentration should be reduced to 60% at 2 h. 

Fuson RL, Kylstra JA, Hochstein P, et al Intravenous Hydrogen Peroxide Infusion as a Means of Extra-pulmonary Oxygenation. Clin. Res. 1967 15 74. 

White CW, Avraham KB, Shanley PF, et al. 1991. Transgenic mice with expression of elevated levels of copper-zinc superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity. J Clin Invest 87(6) 2162-2168. 

Frank, L., 1991, Developmental aspects of experimental pulmonary oxygen toxicity. Free Rad. Biol. Med. 11 463-494. 

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