Pulmonary agents hydrolysis

Si, and stannic tetrachloride. An effective smoke agent, whether it be mechanically dispersed from an aircraft spray tank or vaporized thermally, is a mixt of S trioxide and chlorosulfonic acid (FS smoke agent) which upon hydrolysis forms sulfuric and hydrochloric acid dispersions. Of course, all such formulations are highly corrosive, and, if not outright toxic, then conducive to pulmonary edema... 

To a large extent, therefore, the toxicities of esters tend to be those of their hydrolysis products. Two physical characteristics of many esters that affect their toxicities are relatively high volatility, which promotes exposure by the pulmonary route, and good solvent action, which affects penetration and tends to dissolve body lipids. Many volatile esters exhibit asphyxiant and narcotic action. As expected for compounds that occur naturally in foods, some esters are nontoxic (in reasonable doses). However, some of the synthetic esters, such as allyl acetate, have relatively high toxicities. As an example of a specific toxic effect, vinyl acetate acts as a skin defatting agent. 

DNAse is a human endonuclease, normally present in saliva, urine, pancreatic secretions, and blood. The enzyme catalyzes the hydrolysis of extracellular DNA into oligonucleotides. Aerosoliz recombinant human DNAse (rhDNAse), dornase alfa. Pulmozyme, has been formulated into an inhalation agent for the treatment of pulmonary disease in patients with cy.stic fibrosis (CF). 

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