Pseudomonas aeruginosa antimicrobials effective against

The antimicrobiai activity of CHG is pH dependent, with an optimal use range of 5.5-7.0, a nice consistent match with the body s usuai range of pH. However, the relationship between antimicrobial effectiveness of CHG and pH varies with the microorganism. For example, CHG s antimicrobial activity against Staphylococcus aureus and Escherichia coli increases with an increase in pH, but the reverse is true for Pseudomonas aeruginosa. 

Antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa. Can be used as components of effective industrial antimicrobial agents with low mutagenicity Active against Escherichia coli and Streptococcus aureus and nontoxic toward human epithelial cells. Can be used as highly active antimicrobial agents nontoxic toward plants and mammals... 

Briefly, Tinospora cordifolia reduced mortality associated with intra-abdominal sepsis following caecal ligation. Thus, as compared to a mortality of 66 100% on the fifth day after surgery in untreated rats, 15 days of pretreatment with Tinospora cordifolia alone reduced mortality to 33% and further to 16.6% when combined with metronidazole and gentamicin [19]. This effect was reported to be associated with improved macrophage function. Furthermore, the aqueous extract of Tinospora cordifolia was found to be devoid of in vitro antimicrobial activity against Bacillus subtilis, Bacillus cereus Staphylococcus aureus Pseudomonas aeruginosa and Escherichia coli. Sera obtained from rats (n = 10 each) orally treated with the aqueous extract of Tinospora cordifolia in doses of 100 and 200 mg/kg were also found to have no antibacterial activity [19]. These data further indicated that Tinospora cordifolia was effective in infections due to its immunostimulant effects. 

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