Protein length

Official symbol Official name Other names Chromosome location Genomic location Gene size (bp) Number of exons Transcript length (bp) Protein length (aa)... 

Organism Type of protease Gene Length ofORF (bp) Length of deduced amino acid sequence Length of putative signal peptide Predicted properties of the protein Length Calculated Calculated Mw (kDa) pi Reference... 

Many studies have been carried out on HD mouse models and human material to investigate the basic mechanisms of neurodegeneration of mutant HTT protein [70-72], the effects of mutant HTT protein length [73], the variability in expression changes in different regions of the brain [74], the effects of potential HD drug treatments [13, 75, 76], and to identify potential biomarkers which correlate with the progression of the disease [77]. The next sections will discuss each of these applications in turn. 

The opposite effect would have been produced by a code which contained only one termination codon. In this case the average protein length would have been three times the natural length, and would have produced a world of maxiproteins. 

Increased huntingtin protein length reduces the severity of poly-glutamine-induced gene expression changes in mouse models of Huntington Disease. Hum Mol Genet 11 1939-1951. 

The membrane proteins may be transmembrane, splitting the lipid billayer Fig. (10). In this case the protein length is about lOnm and has hydrophilic and hydrophobic regions. The polar amino acid side chains are exposed to aqueous environment and can... 

The 5 1 rule may be justified on thermodynamic grounds. Thus, Doig and Williams [12] addressed the inconsistencies in I lory s treatment of the entropic contribution to protein denaturation, calculating AAG for denaturation for a cross-linked protein versus its non-cross-linked counterpart. At physiological temperature of 300 K, they estimated A AG 4.4 kcal/mol. This value is essentially independent of protein length and loop size and best represents the insensitivity of experimental values to loop size-dependent configurational entropies [13]. 

Activity Protein Gene Human gene locus Protein length Homology respect ENTl Substrates... 

Coghlan, A. and Wolfe, K. H. (2000) Relationship of codon bias to mRNA concentration and protein length in Saccharomyces cerevisiae. Yeast, 12, 1131-1145. 

Class I Isoform Protein Length Cellular location Example partners Substrate... 

Protein Gene Locus Alleles Protein Length Predicted pp Predicted TMD" Arabidopsis ESTs ... 

We shall not attempt to discuss protein synthesis at any Protein length, only as much as is needed to consider some struc-Biosynthesis tural aspects. 

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