Protein film electrochemistry

Sultana N, Schenkman JB, Rusling JF (2005) Protein film electrochemistry of microsomes genetically enriched in human cytochrome P450 monooxygenases. J Am Chem Soc 127 13460-13461... 

Gates AJ, Kemp GL, To CY, Mann J, Marritt SJ, Mayes AG, Richardson DJ, Butt JN (2011) The relationship between redox enzyme activity and electrochemical potential—cellular and mechanistic implications from protein film electrochemistry. Phys Chem Chem Phys 13 7720-7731. doi 10.1039/C0CP02887H... 

L. Shen and N.F. Hu, Heme protein films with polyamidoamine dendrimer direct electrochemistry and electrocatalysis. BBA-Bioenergetics 1608, 23—33 (2004). 

Hoeben, F.J.M., et al. Toward single-enzyme molecule electrochemistry [NiFe]-hydrogenase protein film voltammetry at nanoelectrodes. ACS Nano 2(12), 2497-2504 (2008)... 

The use of electrodes modified with immobilized redox-active molecules provides a simple methodology by which to study the ultrathin film electrochemistry of water-insoluble redox-active molecules, encouraging the application of such techniques to biomimetic membranes in aqueous media. It is of interest to use monolayer and LB films of enzymes, proteins, and antibodies as biosensors or biomolecular switches because of their high sensitivity for their substrates and antigens, respectively. The formation of thin fullerene films including fullerene-lipid hybrid and fullerene-lipid composite bilayer membranes is of interest both from a fundamental and practical application point of view. Multiwalled carbon nanotubes (MWNTs) and single-walled carbon nanotubes (SWNTs) are novel nanomaterials that have remarkable electronic, mechanical, and thermal properties, and specific functions. Soluble carbon nanotubes in aqueous and organic systems are of interest since their study allows the... 

By the end of the 1980s, it was clear that direct electrochemical observation of the redox chemistry of proteins required control of electrode surface structure and minimization of surface contamination [1-3], In this chapter, we discuss several strategies that combine these critical features with stable immobilization of native proteins in films on electrodes. In Section II, we discuss ordered surfactant films that provide biomembranelike environments for electrochemistry. In Section III, studies on polyion-protein films prepared by casting and grown layer by layer are snmmarized. Section IV presents studies on prototype bioreactors that make nse of electrode-driven enzymelike catalysis. Section V speculates about the future. 

H.-Y. (2005) Direct electrochemistry and electrocatalysis of heme proteins immobilized on self-assembled Zr02 film. Electrochemistry Communications, 7,... 

A large number of studies concerned witli tliiol-tenninated molecules has been directed at tire preparation of tailored organic surfaces, since tlieir importance has been steadily increasing in various applications. Films of o> functionalized alkanetliiols have facilitated fundamental studies of interfacial phenomena, such as adhesion [190, 191], corrosion protection [192], electrochemistry [193], wetting [194], protein adsorjDtion [195, 196] or molecular recognition [197, 198, 199, 200 and 201] to mention only a few. 

Zhou, Y., Hu, N., Zeng, Y. and Rusling, J.F. (2002) Heme protein-clay films Direct electrochemistry and electrochemical catalysis. Langmuir, 18, 211-219. 

---