Protein-Carbohydrate Compounds as Synthetic Antigens

Certain substances called antigens induce the formation of antibodies in serum and other body fluids when they are introduced parenterally into 

REACTIONS OF THE SUGARS WITH SUBSTITUTED HYDRAZINES AND HYDROXYLAMINE  

The reaction of phenylhydrazine with the sugars was discovered by Fischer 202) and was extensively employed in the classical work which established the configuration of the sugars. The products obtained have been widely employed for characterization and identification although they are somewhat difficult to purify, and the melting points are often decomposition points 203). 

Hydrazones. When one mole each of phenylhydrazine and sugar react, phenylhydrazones are formed. Most hydrazones are water soluble, but the mannose phenylhydrazone is so insoluble that it may be used for the quantitative estimation of mannose. The hydrazones are often of value for the separation of sugars, for they may be converted to the original sugars by 

van der Haar, Anleitung zum Nachweis, zur Trennung und Bestim-mung der Monosaccharide und Aldehydsauren. Borntraeger, Berlin, 1920. 

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