Prostate gland physiology

Research in physiology carried out in the 1930s established that the lipid fraction of semen contains small amounts of substances that exert powerful effects on smooth mus cle Sheep prostate glands proved to be a convenient source of this material and yielded a mixture of structurally related substances referred to collectively as prostaglandins We now know that prostaglandins are present m almost all animal tissues where they carry out a variety of regulatory functions... 

In 1935, the Swedish physiologist Ulf Svante von Euler-Chelpin (1905-1983 Nobel Prize in Physiology or Medicine, 1970 his father had been a Nobel laureate as well) (Fig. 5.94) made an unusual discovery he observed that human seminal fluid acts to lower the blood pressure and causes contraction of the uterine tissue. Guided by the assumption that the pharmacological principle was produced in the prostate gland, he called this prostaglandin. [213] Later, it was... 

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