Proprionic acid

Processing and storage equipment for many chemicals, including acetaldehyde, formaldehyde, nylon salt, methyl methacrylate, carbon tetrachloride, glycerol, triacetin, proprionic acid, acetic acid and acetic anhydride, is manufactured from aluminium alloys, primarily because of their excellent corrosion resistance. 

AMPA a-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid... 

Gilron, I., Max, M.B., Lee, G., Booher, S.L., Sang, C.N., Chappell, A.S., and Dionne, R.A., Effects of the 2-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid/kainate antagonist LY293558 on spontaneous and evoked postoperative pain, Clin. Pharmacol. Ther., 68, 320, 2000. 

The excitatoiy amino acids (EAA), glutamate and aspartate, are the principal excitatory neurotransmitters in the brain. They are released by neurons in several distinct anatomical pathways, such as corticofugal projections, but their distribution is practically ubiquitous in the central nervous system. There are both metabotropic and ionotropic EAA receptors. The metabotropic receptors bind glutamate and are labeled mGluRl to mGluRB. They are coupled via G-proteins to phosphoinositide hydrolysis, phospholipase D, and cAMP production. Ionotropic EAA receptors have been divided into three subtypes /V-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid (AMPA), and kainate receptors (Nakanishi 1992). 

At least three types of excitatory amino acid receptors have been identified, termed the NMDA, alpha-amino-3-hydroxy-5-methyl-4-isoxa-zole proprionic acid (AMPA) and kainate receptors according to their affinity for specific excitatory amino acids (see p. 57). Antagonists of some of these receptor types, such as MK 801 and D-2-amino-5-phosphonopentano-ate (AP5), were then shown to protect neurons in vivo against the... 

SYNS a -AMINO-3-INDOLEPROPRIONIC ACID tt-AMINO-INDOLE-3-PROPRIONIC ACID -a-AMINO-3-INDOLEPROPRIONIC ACID 2-Ai nNO-3-INDOL-3-YL-PROPRIONIC ACID EH 121 INDOLE-3-ALANINE l-P-3-INDOLYL LANLNE NCI-C01729 (-)-TRYPTOPHAN 1-TRYPTOPHAN (FCC) TRYPTOPHANE... 

AMINOHYPOXANTHINE see GUOOO a-AMINO-INDOLE-3-PROPRIONIC ACID see TNXOOO a -AMINO-3-INDOLEPROPRIONIC ACID see TNXOOO... 

Fatty-acids, salts and esters Aluminum monostearate, calcium stearate, ethyl oleate, isopropyl myristate, isopropyl palmitate, magnesium stearate, oleic acid, polyoxyl 40 stearate, proprionic acid, sodium stearate, stearic acid, purified stearic acid, and zinc stearate... 

Dissolve 626 g 2-(2-nitrovinyl) furan in 3.13 L 48% HBr and 6.26 L glacial acetic acid and heat on steam bath nine hours. Evaporate in vacuum to 3 L add 3 L water boil decolorize cool and filter. Extract filtrate with 2L CHCI3 and evaporate in vacuum the extract. Add residue to precipitate. Filter out to get 3-Br-isoxazole-5 proprionic acid (I) (recrystallize-benzene-cyclohexane). Dissolve 44 g (I) in 440 ml concentrated sulfuric acid and add 80 g CrOj in 80 ml water dropwise over three hours at 15-20°. Pour onto 800 g ice and extract the aqueous solution with 3X5(X) ml ether. Evaporate in vacuum to get 3-Br-isoxazole-5-COOH (II) (re-crystallize-benzene-toluene). Dissolve 30.7 g (11) and 27 g KOH in 500 ml methanol and stir two hours at 140°. Cool, add 1.5 L water and extract with 3X1.5 L ether. Can decolorize aqueous solution by boiling briefly with carbon, then filtering and acidifying with concentrated HCl. Filter and recrystallize-benzene to get 3-methoxy-isoxazole-5-COOH, which is the analog of (IV) in method 1 and is identical to (11) in method 3 and can be converted to muscimole by either method. 

Proprionic acid derivatives Intolerance of one Usually better... 

CAS 73-22-3 EINECS/ELINCS 200-795-6 Synonyms a -Amino-3-indolepropionic acid l-o-Amino-3-indolepropionic acid 2-Amino-3-indol-3-yl-proprionic acid lndole-3-alanine L-Indole-o-aminopropionic acid 1-P-3-lndolylalanine Trp Tryptophane Classification Amino acid Definition Avail, commercially as the naturally occurring L(+)-enantiomer Empirical C11H12N2O2... 

Both, Y and Y can be cleaved to pUp (and unidentified peptides) by snake venom 3exonuclease. These results exclude phosphoesters like Ser-P or phosphoramidates like nucleotidyl-(5 -N )-Arg or nucleotidyl-(5 -N )-lys as the bond between VPg and ENA. (ii) VPg linked to genome ENA can be iodinated by the Bolton and Hunter reagent ( iodinated 3-(4 hydroxyphenyl) proprionic acid... 

Fig. 2. Structure of myoglobin molecule, after Kendrew et al. (from Ref. 18). Helical segments are indicated by letters from A to H and individual amino acids are shown by number. The heme is in the upper center of the figure, above the C-helix. The iron atom, shown as a large black circle, is coordinated to the F8 histidine. The E7 histidine is too remote for coordination to occur. M, V, and P on the heme indicate methyl, vinyl and proprionic acid side chains.

Complex organic compounds, such as cellulose and lignin, are broken down into simpler salts and acids, typified by acetic acid, proprionic acid and pyruvic acid or alcohols. This process is known as acidification... 

Antagonists of 2-amino-3-(3-hydroxy-5-methyl-4-isoxazoyl)proprionic acid (subset of excitatory amino acid receptors in the brain, of interest for treatment of neurodegenerative disease)... 

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