Promoter patatin

In a very recent study in potatoes, inhibition of LCYE accumulation was accomplished by an antisense LcyE driven by the patatin promoter and allowed rechanneling of lycopene toward the P-carotene branch of the pathway to produce up to 14-fold increased levels of P-carotene as well as up to 2.5-fold increased total carotenoids. RNAi and TILLING for manipulation of carotenogenesis have yet to be reported, but these new techniques for suppression of function and generation and selection of allelic diversity are likely to impact future research and production of varieties with enhanced pigment accumulation. 

Rocha-Sosa M, Sonnewald U, Frommer W, Stratman M, Schell J, Willmitzer L (1989) Both developmental and metabolic signals activate the promoter of class I patatin gene. EMBO J 8 23-29... 

Developmental promoters that have been commonly used for vaccine production include patatin and E8 promoters derived from potato and tomato, respectively. Patatin is one of the major soluble proteins in potato tubers and is encoded by a multigene family. The patatin promoter is tuber-specific the protein is expressed in tubers but not in leaves (Grierson et al., 1994). Patatin has been shown to express vaccine protein in potato tubers at levels greater than the CaMV 35S promoter (Rocha-Sosa et al., 1989). 

Rocha-Sosa, M., Sonnewald, U., Frommer, W., Stratmann, M., Schell, J., and Willmitzer, L. (1989). Both developmental and metabohc signals activate the promoter of a class 1 patatin gene. EMBO J. 8(1) 23-29. 

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